Reactive oxygen species, toxicity, oxidative stress, and antioxidants: Chronic diseases and aging

K Jomova, R Raptova, SY Alomar, SH Alwasel… - Archives of …, 2023 - Springer
A physiological level of oxygen/nitrogen free radicals and non-radical reactive species
(collectively known as ROS/RNS) is termed oxidative eustress or “good stress” and is …

[HTML][HTML] Essential metals in health and disease

K Jomova, M Makova, SY Alomar, SH Alwasel… - Chemico-biological …, 2022 - Elsevier
In total, twenty elements appear to be essential for the correct functioning of the human
body, half of which are metals and half are non-metals. Among those metals that are …

An overview of oxidative stress, neuroinflammation, and neurodegenerative diseases

DM Teleanu, AG Niculescu, II Lungu, CI Radu… - International journal of …, 2022 - mdpi.com
Oxidative stress has been linked with a variety of diseases, being involved in the debut
and/or progress of several neurodegenerative disorders. This review intends to summarize …

Molecular and cellular mechanisms underlying the pathogenesis of Alzheimer's disease

T Guo, D Zhang, Y Zeng, TY Huang, H Xu… - Molecular …, 2020 - Springer
Alzheimer's disease (AD) is the most common neurodegenerative disorder seen in age-
dependent dementia. There is currently no effective treatment for AD, which may be …

Amyloid beta in aging and Alzheimer's disease

U Sehar, P Rawat, AP Reddy, J Kopel… - International journal of …, 2022 - mdpi.com
Alzheimer's disease (AD), is a progressive neurodegenerative disease that affects behavior,
thinking, learning, and memory in elderly individuals. AD occurs in two forms, early onset …

[HTML][HTML] Myricetin: A review of the most recent research

X Song, L Tan, M Wang, C Ren, C Guo, B Yang… - Biomedicine & …, 2021 - Elsevier
Myricetin (MYR) is a flavonoid compound widely found in many natural plants including
bayberry. So far, MYR has been proven to have multiple biological functions and it is a …

The molecular mechanisms of copper metabolism and its roles in human diseases

J Chen, Y Jiang, H Shi, Y Peng, X Fan, C Li - Pflügers Archiv-European …, 2020 - Springer
Copper is an essential element in cells; it can act as either a recipient or a donor of
electrons, participating in various reactions. However, an excess of copper ions in cells is …

[HTML][HTML] Kaempferol, a potential neuroprotective agent in neurodegenerative diseases: From chemistry to medicine

S Jin, L Zhang, L Wang - Biomedicine & Pharmacotherapy, 2023 - Elsevier
Neurodegenerative diseases (NDDs) encompass a range of conditions that involve
progressive deterioration and dysfunction of the nervous system. Some of the common …

Role of reactive oxygen species in aging and age-related diseases: A review

MI Anik, N Mahmud, AA Masud, MI Khan… - ACS Applied Bio …, 2022 - ACS Publications
Research on the role of reactive oxygen species (ROS) in the aging process has advanced
significantly over the last two decades. In light of recent findings, ROS takes part in the aging …

Oxidative stress in alzheimer's disease: A review on emergent natural polyphenolic therapeutics

L Cassidy, F Fernandez, JB Johnson, M Naiker… - … therapies in medicine, 2020 - Elsevier
Objectives The aim of this research was to review the literature on Alzheimer's disease (AD)
with a focus on polyphenolics as antioxidant therapeutics. Design This review included a …