[HTML][HTML] Licorice (Glycyrrhiza glabra L.)-derived phytochemicals target multiple signaling pathways to confer oncopreventive and oncotherapeutic effects

HS Tuli, VK Garg, JK Mehta, G Kaur… - OncoTargets and …, 2022 - ncbi.nlm.nih.gov
Cancer is a highly lethal disease, and its incidence has rapidly increased worldwide over
the past few decades. Although chemotherapeutics and surgery are widely used in clinical …

Glycyrrhizae Radix et Rhizoma: The popular occurrence of herbal medicine applied in classical prescriptions

L He, Q Kang, Y Zhang, M Chen, Z Wang… - Phytotherapy …, 2023 - Wiley Online Library
Abstract Glycyrrhizae Radix et Rhizoma is a well‐known herbal medicine with a wide range
of pharmacological functions that has been used throughout Chinese history. This review …

[HTML][HTML] Licorice flavonoid alleviates gastric ulcers by producing changes in gut microbiota and promoting mucus cell regeneration

Y Wu, Y Guo, T Huang, D Huang, L Liu, C Shen… - Biomedicine & …, 2023 - Elsevier
Licorice flavonoid (LF) is the main component of Glycyrrhizae Radix et Rhizoma, a
“medicine food homology” herbal medicine, which has anti-digestive ulcer activity, but the …

Isoliquiritigenin from licorice flavonoids attenuates NLRP3-mediated pyroptosis by SIRT6 in vascular endothelial cells

J He, Y Deng, L Ren, Z Jin, J Yang, F Yao, Y Liu… - Journal of …, 2023 - Elsevier
Ethnopharmacologic relevance Licorice is a traditional Chinese medicine that has been
used for cardiovascular diseases. Recent studies found that supplementation with licorice …

Licochalcone B induces ROS-dependent apoptosis in oxaliplatin-resistant colorectal cancer cells via p38/JNK MAPK signaling

AW Kwak, WK Kim, SO Lee, G Yoon, SS Cho, KT Kim… - Antioxidants, 2023 - mdpi.com
Licochalcone B (LCB) exhibits anticancer activity in oral cancer, lung cancer, and
hepatocellular carcinoma cells. However, little is known about its antitumor mechanisms in …

Glycyrrhiza uralensis Fisch. alleviates dextran sulfate sodium-induced colitis in mice through inhibiting of NF-κB signaling pathways and modulating intestinal …

G Shi, J Kong, Y Wang, Z Xuan, F Xu - Journal of Ethnopharmacology, 2022 - Elsevier
Ethnopharmacological relevance Licorice is widely used in traditional Chinese Medicine
(TCM) for compound compatibility, which could reduce toxicity and increase efficacy of …

[HTML][HTML] Mechanism insight on licorice flavonoids release from Carbopol hydrogels: Role of “release steric hindrance” and drug solubility in the release medium

Z Wang, Y Hu, Y Xue, Z Zhu, Y Wu, Q Zeng… - European Journal of …, 2022 - Elsevier
The present study was to systematically evaluate different licorice flavonoids (LFs)
compounds release behaviors from the single payload hydrogel and LFs extracts hydrogels …

Licochalcone A protects against LPS‐induced inflammation and acute lung injury by directly binding with myeloid differentiation factor 2 (MD2)

W Zhu, M Wang, L Jin, B Yang, B Bai… - British Journal of …, 2023 - Wiley Online Library
Background and Purpose Acute lung injury (ALI)/acute respiratory distress syndrome
(ARDS) is a challenging clinical syndrome that leads to various respiratory sequelae and …

Isolation, characterization, pharmacology and biopolymer applications of licorice polysaccharides

NU Ain, S Wu, X Li, D Li, Z Zhang - Materials, 2022 - mdpi.com
Licorice is known as “Gan-Cao” in traditional Chinese Medicine (TCM), belonging to the
genus Glycyrrhiza (Family: Fabaceae/Leguminosae). It has a long medicinal history and …

Variation in antioxidant enzyme activity and key gene expression during fruit development of blackberry and blackberry–raspberry hybrids

X Huang, Y Wu, S Zhang, H Yang, W Wu, L Lyu, W Li - Food Bioscience, 2023 - Elsevier
Blackberry (Rubus spp.) belongs to the Rubus genus in the Rosaceae family, and its fruits
are rich in nutrients and function in exerting antioxidant effects. Based on this, the fruits …