Sodium‐glucose cotransporter‐2 inhibitors and kidney outcomes in real‐world type 2 diabetes populations: a systematic review and meta‐analysis of observational …

AK Forbes, RJ Suckling, W Hinton… - Diabetes, Obesity …, 2023 - Wiley Online Library
Aim To conduct a systematic review of observational studies to explore the real‐world
kidney benefits of sodium‐glucose cotransporter‐2 (SGLT2) inhibitors in a large and diverse …

SGLT2 inhibition via empagliflozin improves endothelial function and reduces mitochondrial oxidative stress: insights from frail hypertensive and diabetic patients

P Mone, F Varzideh, SS Jankauskas, A Pansini… - …, 2022 - Am Heart Assoc
Background: Frailty is a multidimensional condition often diagnosed in older adults with
hypertension and diabetes, and both these conditions are associated with endothelial …

Treatment effect heterogeneity following type 2 diabetes treatment with GLP1-receptor agonists and SGLT2-inhibitors: a systematic review

KG Young, EH McInnes, RJ Massey… - Communications …, 2023 - nature.com
Background A precision medicine approach in type 2 diabetes requires the identification of
clinical and biological features that are reproducibly associated with differences in clinical …

Comparison of cardiovascular outcomes between SGLT2 inhibitors in diabetes mellitus

Y Suzuki, H Kaneko, A Okada, H Itoh… - Cardiovascular …, 2022 - Springer
Background There have been scarce data comparing cardiovascular outcomes between
individual sodium-glucose cotransporter-2 (SGLT2) inhibitors. We aimed to compare the …

Kidney outcomes in patients with diabetes mellitus did not differ between individual sodium-glucose cotransporter-2 inhibitors

Y Suzuki, H Kaneko, A Okada, S Matsuoka, K Fujiu… - Kidney International, 2022 - Elsevier
Data comparing kidney outcomes between individual sodium-glucose cotransporter-2
(SGLT2) inhibitors are limited. Here, we aimed to compare the subsequent risk of …

Introduction to matching in case-control and cohort studies

M Iwagami, T Shinozaki - Annals of Clinical Epidemiology, 2022 - jstage.jst.go.jp
Matching is a technique through which patients with and without an outcome of interest (in
case-control studies) or patients with and without an exposure of interest (in cohort studies) …

Update on hypertension research in 2021

M Mogi, T Maruhashi, Y Higashi, T Masuda… - Hypertension …, 2022 - nature.com
In 2021, 217 excellent manuscripts were published in Hypertension Research. Editorial
teams greatly appreciate the authors' contribution to hypertension research progress. Here …

SGLT-2 inhibitors in nephrotic-range proteinuria: emerging clinical evidence

Z Kalay, OE Sahin, S Copur, S Danacı… - Clinical Kidney …, 2023 - academic.oup.com
ABSTRACT Sodium-glucose cotransporter-2 (SGLT-2) inhibitors are a class of novel oral
anti-hyperglycemic agents which are increasingly used in clinical practice. SGLT-2 inhibitors …

Current status of the rapid decline in renal function due to diabetes mellitus and its associated factors: analysis using the National Database of Health Checkups in …

M Fujii, Y Ohno, A Ikeda, K Godai, Y Li… - Hypertension …, 2023 - nature.com
The increasing number of patients undergoing dialysis due to diabetes mellitus (DM) is
causing serious economic problems, and its reduction is an urgent policy issue in developed …

Association between SGLT2 inhibitors vs DPP4 inhibitors and renal outcomes among patients with type 2 diabetes

PCM Au, KCB Tan, BMY Cheung… - The Journal of …, 2022 - academic.oup.com
Context Diabetic kidney disease is a major burden among diabetic patients. Sodium-
glucose cotransporter 2 inhibitors (SGLT2is) were shown to reduce renal outcomes in …