Preparation, applications, and challenges of functional DNA nanomaterials

L Zhang, M Chu, C Ji, J Tan, Q Yuan - Nano Research, 2023 - Springer
As a carrier of genetic information, DNA is a versatile module for fabricating nanostructures
and nanodevices. Functional molecules could be integrated into DNA by precise base …

Fast-Track Synthesis of DNA-Functionalized Gold Nanoparticles for Biosensing Applications

Z Ye, W Liao, Z Deng, L Wang, B Wen, D Zhang… - TrAC Trends in …, 2024 - Elsevier
DNA-functionalized nanomaterials represent the cutting edge of the convergence between
nanoscience and life sciences. The gold nanoparticles (AuNPs), with their versatile …

Simultaneous imaging and visualizing the association of survivin mRNA and telomerase in living cells by using a dual-color encoded DNA nanomachine

C Zhao, L Zhang, Y Hu, C Nie, TT Chen… - Analytical …, 2023 - ACS Publications
Simultaneous imaging and especially visualizing the association of survivin mRNA and
telomerase in living cells are of great value for the diagnosis and prognosis of cancer …

A fluorescent aptasensor based on ZIF-8@ PdNCs and DNA-AgNCs for tobramycin detection in milk

X Wang, R Xu, Y Tian, X Gao, W Zhang, Z Sun… - Sensors and Actuators B …, 2023 - Elsevier
A novel ratiometric fluorescent aptasensor was constructed utilizing ZIF-8-encapsulated
palladium nanoclusters (ZIF-8@ PdNCs) as reference signals that emit blue fluorescence …

Porous Framework Materials for Bioimaging and Cancer Therapy

M Jin, Y Zhao, ZJ Guan, Y Fang - Molecules, 2023 - mdpi.com
Cancer remains one of the most pressing diseases in the world. Traditional treatments,
including surgery, chemotherapy, and radiotherapy still show certain limitations. Recently …

Tetrahedral DNA frameworks for biosensing and imaging analysis in living cells

Z Qi, C Wei, F Zhang, Z Wang, X Zuo - Nano Today, 2024 - Elsevier
DNA is the primary genetic material that is highly compatible with biological system, and its
intrinsic property of complementary base pairing can be programmed for analysis. However …

Construction of single-molecule counting-based biosensors for DNA-modifying enzymes: A review

Q Zhang, J Hu, D Li, JG Qiu, BH Jiang, C Zhang - Analytica Chimica Acta, 2024 - Elsevier
DNA-modifying enzymes act as critical regulators in a wide range of genetic functions (eg,
DNA damage & repair, DNA replication), and their aberrant expression may interfere with …

Improving DNA nanostructure stability: A review of the biomedical applications and approaches

M Nasiri, M Bahadorani, K Dellinger… - International Journal of …, 2024 - Elsevier
DNA's programmable, predictable, and precise self-assembly properties enable structural
DNA nanotechnology. DNA nanostructures have a wide range of applications in drug …

DNA-functionalized metal or metal-containing nanoparticles for biological applications

H Chu, B Liu, H Duan, Z Liu, Y Liu - Dalton Transactions, 2024 - pubs.rsc.org
The conjugation of DNA molecules with metal or metal-containing nanoparticles (M/MC
NPs) has resulted in a number of new hybrid materials, eliciting a diverse range of novel …

An unique DNA junction scaffold-based electrochemical sensing platform achieving multilevel signal responses for amplified multiplexed nucleic acid analysis and …

D Qu, Z Gu, J Wu, L Wang, S Liu - Sensors and Actuators B: Chemical, 2023 - Elsevier
Herein, a DNA junction scaffold structure was exploited as the only immobilization probe to
construct a simple and multifunctional electrochemical sensing platform. The programmable …