[HTML][HTML] Pathophysiology, phenotypes and management of type 2 diabetes mellitus in Indian and Chinese populations

C Ke, KMV Narayan, JCN Chan, P Jha… - Nature Reviews …, 2022 - nature.com
Nearly half of all adults with type 2 diabetes mellitus (T2DM) live in India and China. These
populations have an underlying predisposition to deficient insulin secretion, which has a key …

SCORE2 risk prediction algorithms: new models to estimate 10-year risk of cardiovascular disease in Europe

ESC Cardiovasc Risk Collaboration… - European Heart …, 2021 - research.rug.nl
Aims The aim of this study was to develop, validate, and illustrate an updated prediction
model (SCORE2) to estimate 10-year fatal and non-fatal cardiovascular disease (CVD) risk …

[HTML][HTML] Pathophysiology of type 2 diabetes mellitus

U Galicia-Garcia, A Benito-Vicente, S Jebari… - International journal of …, 2020 - mdpi.com
Type 2 Diabetes Mellitus (T2DM), one of the most common metabolic disorders, is caused
by a combination of two primary factors: defective insulin secretion by pancreatic β-cells and …

The Lancet Commission on diabetes: using data to transform diabetes care and patient lives

JCN Chan, LL Lim, NJ Wareham, JE Shaw, TJ Orchard… - The Lancet, 2020 - thelancet.com
Executive summary 2020 will go down in history as the year when the global community was
awakened to the fragility of human health and the interdependence of the ecosystem …

[HTML][HTML] Interpreting global trends in type 2 diabetes complications and mortality

MK Ali, J Pearson-Stuttard, E Selvin, EW Gregg - Diabetologia, 2022 - Springer
International trends in traditional diabetes complications (cardiovascular, renal, peripheral
vascular, ophthalmic, hepatic or neurological diseases) and mortality rates are poorly …

Global burden of 5 major types of gastrointestinal cancer

M Arnold, CC Abnet, RE Neale, J Vignat… - Gastroenterology, 2020 - Elsevier
Background & Aims There were an estimated 4.8 million new cases of gastrointestinal (GI)
cancers and 3.4 million related deaths, worldwide, in 2018. GI cancers account for 26% of …

[HTML][HTML] Magnitude, demographics and dynamics of the effect of the first wave of the COVID-19 pandemic on all-cause mortality in 21 industrialized countries

V Kontis, JE Bennett, T Rashid, RM Parks… - Nature medicine, 2020 - nature.com
Abstract The Coronavirus Disease 2019 (COVID-19) pandemic has changed many social,
economic, environmental and healthcare determinants of health. We applied an ensemble …

[HTML][HTML] Adipose tissue distribution, inflammation and its metabolic consequences, including diabetes and cardiovascular disease

A Chait, LJ Den Hartigh - Frontiers in cardiovascular medicine, 2020 - frontiersin.org
Adipose tissue plays essential roles in maintaining lipid and glucose homeostasis. To date
several types of adipose tissue have been identified, namely white, brown, and beige, that …

Pancreatic β-cells in type 1 and type 2 diabetes mellitus: different pathways to failure

DL Eizirik, L Pasquali, M Cnop - Nature Reviews Endocrinology, 2020 - nature.com
Loss of functional β-cell mass is the key mechanism leading to the two main forms of
diabetes mellitus—type 1 diabetes mellitus (T1DM) and type 2 diabetes mellitus (T2DM) …

European Society of Cardiology: cardiovascular disease statistics 2019

A Timmis, N Townsend, CP Gale, A Torbica… - European heart …, 2020 - academic.oup.com
Aims The 2019 report from the European Society of Cardiology (ESC) Atlas provides a
contemporary analysis of cardiovascular disease (CVD) statistics across 56 member …