Purpose Vitiligo-like depigmentation in patients with melanoma may be associated with
more favorable clinical outcome. We conducted a systematic review of patients with stage III …

Abstract The Ras/Raf/Mitogen-activated protein kinase/ERK kinase (MEK)/extracellular-
signal-regulated kinase (ERK) cascade couples signals from cell surface receptors to …

Dendritic cells (DCs) have shown great potential as a component or target in the landscape
of cancer immunotherapy. Different in vivo and ex vivo strategies of DC vaccine generation …

Dendritic cells (DCs) occupy a central position in the immune system, orchestrating a wide
repertoire of responses that span from the development of self-tolerance to the elicitation of …

Dendritic cell (DC) immunotherapy has shown significant promise in animal studies as a
potential treatment for cancer. Its application in the clinic depends on the results of human …

In the present study, we assessed the feasibility, toxicity, immunologic response, and clinical
efficacy of vaccination with allogeneic dendritic cell (DC)/tumor fusions in patients with …

The use of tumor antigen-loaded dendritic cells (DC) is one of the most promising
approaches to inducing a tumor-specific immune response. We compared electroporation of …

Hybrid cells generated by fusing dendritic cells with tumor cells (DC-TC) are currently being
evaluated as cancer vaccines in preclinical models and human immunization trials. In this …

Immunotherapy based on whole cancer cell vaccines is regarded as a promising avenue for
cancer treatment. However, limited efficacy in the first human clinical trials calls for more …

Since its first clinical application, 120 years ago, radiotherapy evolved into a major anti-
cancer treatment modality, offering high cure rates in many human malignancies. During the …