Artificial intelligence (AI) and other data-driven technologies hold great promise to transform
healthcare and confer the predictive power essential to precision medicine. However, the …

Synovial tissue inflammation is a hallmark of rheumatoid arthritis (RA). Recent work has
identified prominent pathogenic cell states in inflamed RA synovial tissue, such as T …

As important commensals in the chicken intestine, Bacteroides are essential complex
carbohydrate degraders, and short-chain fatty acid (SCFA) producers that are highly …

Molybdenum (Mo) as essential micronutrient for plants, acts as active component of
molybdenum cofactor (Moco). Core metabolic processes like nitrate assimilation or abscisic …

Infections can lead to persistent or long-term symptoms and diseases such as shingles after
varicella zoster, cancers after human papillomavirus, or rheumatic fever after streptococcal …

Brown adipose tissue (BAT) regulates metabolic physiology. However, nearly all
mechanistic studies of BAT protein function occur in a single inbred mouse strain, which has …

The growing number of available single-cell gene expression datasets from different species
creates opportunities to explore evolutionary relationships between cell types across …

Commitment to specific cell lineages is critical for mammalian embryonic development.
Lineage determination, differentiation, maintenance, and organogenesis result in diverse life …

Single-cell studies have delineated cellular diversity and uncovered increasing numbers of
previously uncharacterized cell types in complex tissues. Thus, synthesizing growing …

Various cellular quality control mechanisms support proteostasis. While, ribosome-
associated chaperones prevent the misfolding of nascent chains during translation …