Cryoprotectants: A review of the actions and applications of cryoprotective solutes that modulate cell recovery from ultra-low temperatures

GD Elliott, S Wang, BJ Fuller - Cryobiology, 2017 - Elsevier
Cryopreservation has become a central technology in many areas of clinical medicine,
biotechnology, and species conservation within both plant and animal biology …

Dimethyl sulfoxide: a central player since the dawn of cryobiology, is efficacy balanced by toxicity?

M Awan, I Buriak, R Fleck, B Fuller, A Goltsev… - Regenerative …, 2020 - Taylor & Francis
Dimethyl sulfoxide (DMSO) is the cryoprotectant of choice for most animal cell systems since
the early history of cryopreservation. It has been used for decades in many thousands of cell …

Polymer mimics of biomacromolecular antifreezes

CI Biggs, TL Bailey, B Graham, C Stubbs… - Nature …, 2017 - nature.com
Antifreeze proteins from polar fish species are remarkable biomacromolecules which
prevent the growth of ice crystals. Ice crystal growth is a major problem in cell/tissue …

[HTML][HTML] Industrializing autologous adoptive immunotherapies: manufacturing advances and challenges

RK Iyer, PA Bowles, H Kim, A Dulgar-Tulloch - Frontiers in medicine, 2018 - frontiersin.org
Cell therapy has proven to be a burgeoning field of investigation, evidenced by hundreds of
clinical trials being conducted worldwide across a variety of cell types and indications. Many …

Polyampholytes as emerging macromolecular cryoprotectants

C Stubbs, TL Bailey, K Murray, MI Gibson - Biomacromolecules, 2019 - ACS Publications
Cellular cryopreservation is a platform technology which underpins cell biology,
biochemistry, biomaterials, diagnostics, and the cold chain for emerging cell-based …

Gut-derived metabolite indole-3-propionic acid modulates mitochondrial function in cardiomyocytes and alters cardiac function

M Gesper, ABH Nonnast, N Kumowski, R Stoehr… - Frontiers in …, 2021 - frontiersin.org
Background: The gut microbiome has been linked to the onset of cardiometabolic diseases,
in part facilitated through gut microbiota-dependent metabolites such as trimethylamine-N …

Antiviral effect of methylated flavonol isorhamnetin against influenza

AA Dayem, HY Choi, YB Kim, SG Cho - PloS one, 2015 - journals.plos.org
Influenza is an infectious respiratory disease with frequent seasonal epidemics that causes
a high rate of mortality and morbidity in humans, poultry, and animals. Influenza is a serious …

Whole-genome screens reveal regulators of differentiation state and context-dependent migration in human neutrophils

NM Belliveau, MJ Footer, E Akdoǧan… - Nature …, 2023 - nature.com
Neutrophils are the most abundant leukocyte in humans and provide a critical early line of
defense as part of our innate immune system. We perform a comprehensive, genome-wide …

Mitochondrial Targeting and Imaging with Small Organic Conjugated Fluorophores: A Review

H Crawford, M Dimitriadi, J Bassin… - … A European Journal, 2022 - Wiley Online Library
The last decade has seen an increasingly large number of studies reporting on the
development of novel small organic conjugated systems for mitochondrial imaging …

Effect of copper ion concentration on bacteria and cells

L Fowler, H Engqvist, C Öhman-Mägi - Materials, 2019 - mdpi.com
In the oral cavity, dental implants—most often made of commercially pure titanium—come in
contact with bacteria, and antibacterial management has been researched extensively to …