Zinc finger proteins and ATP‐binding cassette transporter‐dependent multidrug resistance
S Barzegar, S Pirouzpanah - European Journal of Clinical …, 2024 - Wiley Online Library
Background Multidrug resistance (MDR) remains a significant challenge in cancer treatment,
leading to poor clinical outcomes. Dysregulation of ATP‐binding cassette (ABC) transporters …
leading to poor clinical outcomes. Dysregulation of ATP‐binding cassette (ABC) transporters …
Polyphenols and posterior segment eye diseases: effects on angiogenesis, invasion, migration and epithelial-mesenchymal transition
M Caban, U Lewandowska - Food Reviews International, 2023 - Taylor & Francis
Posterior segment eye diseases are a major cause of visual impairment worldwide. If left
untreated, most of them lead to partial or complete blindness. The formation of new …
untreated, most of them lead to partial or complete blindness. The formation of new …
Polyphenols and its effect on the immune system
The mainstay of good health is well functioning and strong immune system which involves
interaction between acquired and innate components of the immune system that leads to …
interaction between acquired and innate components of the immune system that leads to …
[HTML][HTML] The AKT inhibitor MK2206 suppresses airway inflammation and the pro‑remodeling pathway in a TDI‑induced asthma mouse model
H Cui, Y Cheng, Y He, W Cheng… - Molecular …, 2020 - spandidos-publications.com
The cellular and molecular mechanisms via which MK2206, an AKT inhibitor, prevents the
activation of AKT in toluene diisocyanate (TDI)‑induced asthma remain unclear. Thus, the …
activation of AKT in toluene diisocyanate (TDI)‑induced asthma remain unclear. Thus, the …
Nrf2 regulates downstream genes by targeting miR-29b in severe asthma and the role of grape seed proanthocyanidin extract in a murine model of steroid-insensitive …
Y Qian, Y Sun, Y Chen, Z Mao, Y Shi, D Wu… - Pharmaceutical …, 2022 - Taylor & Francis
Context Grape seed proanthocyanidin extract (GSPE) is effective in treating severe asthma
(SA). Objective To examine the relationship between Nrf2-miR-29b axis and SA, and to …
(SA). Objective To examine the relationship between Nrf2-miR-29b axis and SA, and to …
[HTML][HTML] Bridging the gap: Integrating exercise mimicry into chronic disease management through suppressing chronic inflammation
M Nasb, F Li, L Dayoub, T Wu, M Wei… - Journal of Advanced …, 2024 - Elsevier
Background Chronic inflammation is a common hallmark of many chronic diseases.
Although exercise holds paramount importance in preventing and managing chronic …
Although exercise holds paramount importance in preventing and managing chronic …
Epigallocatechin-3-gallate protects against the exacerbation of allergic eosinophilic inflammation associated with obesity in mice
DM André, CM Horimoto, MC Calixto… - International …, 2018 - Elsevier
Obesity is linked to worse asthma symptoms. Epigallocatechin-3-gallate (EGCG) reduces
airway inflammation, but no study investigated the effects of EGCG on obesity-associated …
airway inflammation, but no study investigated the effects of EGCG on obesity-associated …
Green tea extract suppresses airway inflammation via oxidative stress-driven MAPKs/MMP-9 signaling in asthmatic mice and human airway epithelial cells
JW Kim, JH Kim, JS Jeong, CY Kim, EH Chung… - Frontiers in …, 2024 - frontiersin.org
Introduction The anti-inflammatory effect of green tea extract (GTE) has been confirmed in
asthmatic mice, however, the pharmacological mechanism is not fully elucidated. Methods …
asthmatic mice, however, the pharmacological mechanism is not fully elucidated. Methods …
Network pharmacology study of yuebi plus banxia decoction in treating asthma
WJ Song, Z Hao - World Journal of Traditional Chinese Medicine, 2021 - journals.lww.com
Objective: The objective of the study was to study the potential biological mechanism of
Yuebi plus Banxia Decoction (YBD) in the treatment of asthma based on network …
Yuebi plus Banxia Decoction (YBD) in the treatment of asthma based on network …
Epigallocatechin-3-gallate (EGCG) inhibits aggregation of pulmonary fibrosis associated mutant surfactant protein A2 via a proteasomal degradation pathway
Y Quan, L Li, L Dong, S Wang, X Jiang, T Zhang… - … International Journal of …, 2019 - Elsevier
Abstract Background/aims Epigallocatechin-3-gallate (EGCG), a major catechin found in
green tea, plays an important anti-tumor role and is involved in various other biological …
green tea, plays an important anti-tumor role and is involved in various other biological …