Enaminone, Enaminoesters, and Related Compounds in the Metal‐Free Synthesis of Pyridines and Fused Pyridines

B Stanovnik - European Journal of Organic Chemistry, 2019 - Wiley Online Library
This minireview presents the synthesis and applications of enaminones, enaminoesters, and
related compounds. A metal‐free synthesis of pyridines and fused pyridines, pyridyl …

One-Pot Sequential Hydroamination Protocol for N-Heterocycle Synthesis: One Method To Access Five Different Classes of Tri-Substituted Pyridines

V Verma, LL Schafer - The Journal of Organic Chemistry, 2023 - ACS Publications
Tri-substituted pyridines are important scaffolds that can be found in a plethora of
commercially available drugs. A one-pot general method for the selective synthesis of less …

Synthesis of pyridines with an amino acid residue by [2+ 2] cycloadditions of electron-poor acetylenes on enaminone systems derived from N-Boc protected amino …

B Prek, J Bezenšek, B Stanovnik - Tetrahedron, 2017 - Elsevier
In this paper we present a pyridine synthesis, starting from N-protected amino acids. Amino
acids are firstly converted to an ynone system, which is later converted to an enaminone …

Terminal acetylenic iminium salts–synthesis and reactivity

M Keim, P Kratzer, H Derksen… - European Journal of …, 2019 - Wiley Online Library
Various types of terminal acetylenic iminium triflates (propyne iminium salts) featuring a
ketiminium or an aldiminium group have been prepared for the first time by protiodesilylation …

Reactions of a 3‐Phenyl‐1‐trifluoromethyl‐prop‐2‐yne Iminium Salt with Furans, Thiophenes, and Pyrroles

T Schneider, G Heinrich, R Koch… - European Journal of …, 2021 - Wiley Online Library
Reactions of a novel propyne iminium salt, N, N‐dimethyl 3‐phenyl‐1‐trifluoromethyl‐
propyne iminium triflate, with electron‐rich heteroaromatic ring systems (furans, thiophenes …

[PDF][PDF] 1-Fluoralkyl-prop-2-in-1-imine und-1-iminium-Salze: Synthesen und Cycloadditionen

M Schiwek - 2023 - oparu.uni-ulm.de
1-Fluoralkyl-prop-2-in-1-N, N-dimethyliminium-Salze wurden durch N-Methylierung von
Alkinylfluoralkyl-N-methylketiminen erhalten. Sie repräsentieren eine neue und aufgrund …

[2+ 2] Cycloadditions of electron-poor acetylenes to endocyclic enaminones: ring-expansion reactions

J Bezenšek, B Prek, U Grošelj, M Počkaj, J Svete… - Tetrahedron, 2015 - Elsevier
Reactions of cyclic enaminones, derived from cyclic five-and six-membered 1, 3-diones, and
dimethyl acetylenedicarboxylate (DMAD) under microwave irradiation produced a mixture of …

A simple synthesis of dimethyl 2-[(Z)-3-amino-1-oxo-1-(substituted)but-2-en-2-yl]fumarates: potential intermediates in the synthesis of polysubstituted five- and six …

R Šinkovec, U Grošelj, B Prek, M Počkaj… - … Für Naturforschung B, 2016 - degruyter.com
In this communication, a simple synthesis of dimethyl 2-[(Z)-3-amino-1-oxo-1-(substituted)
but-2-en-2-yl] fumarates is described. Methyl ketones were transformed by treatment with N …

Thermal metal-free [2+ 2] cycloaddition of acetylenedicarboxylates to polysubstituted butadienes

B Prek, M Počkaj, W Kantlehner… - … für Naturforschung B, 2018 - degruyter.com
Thermal metal-free [2+2] cycloaddition of acetylenedicarboxylates to polysubstituted butadienes
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