No causal association between the volume of strenuous exercise and coronary atherosclerosis: a two-sample Mendelian randomization study
Z Xiao, G Huang, G Li, H Wang, X Zheng… - Frontiers in …, 2024 - frontiersin.org
Objective Several observational studies have shown that high-volume and high-intensity
exercise training increases the prevalence and severity of coronary atherosclerosis, but the …
exercise training increases the prevalence and severity of coronary atherosclerosis, but the …
Genetically predicted physical activity is associated with lower serum urate concentrations
Y Guan, J Wei, L Meng, Y Li, T Wang, D Chen… - Genes & Genomics, 2022 - Springer
Background Physical activity (PA) is considered to play an important role in the reduced gout
risk. However, the epidemiology results are inconsistent and causality remains unclear …
risk. However, the epidemiology results are inconsistent and causality remains unclear …
The non‐causative role of abnormal serum uric acid in intervertebral disc degeneration: A Mendelian randomization study
YT Cai, YX Li, LR Wang, L Mo, Y Li, SC Zhang - JOR spine, 2024 - Wiley Online Library
Background Intervertebral disc degeneration (IDD) is a common musculoskeletal disorder
that contributes significantly to disability and healthcare costs. Serum urate concentration …
that contributes significantly to disability and healthcare costs. Serum urate concentration …
Alcohol Use and Use Disorder and Cancer Risk: Perspective on Causal Inference
H Zhou, V Vasiliou - Complex Psychiatry, 2022 - karger.com
Alcoholic beverages are classified as carcinogenic to humans by the International Agency
for Research on Cancer. Globally, nearly 5.5% of all cancers are attributable to alcohol use …
for Research on Cancer. Globally, nearly 5.5% of all cancers are attributable to alcohol use …
Proteome-Wide Multicenter Mendelian Randomization Analysis to Identify Novel Therapeutic Targets for Lung Cancer
K Wang, H Yi, Y Wang, D Jin, G Zhang… - Archivos de …, 2024 - Elsevier
Introduction Lung cancer (LC) remains a leading cause of cancer mortality worldwide,
underscoring the urgent need for novel therapeutic targets. The integration of Mendelian …
underscoring the urgent need for novel therapeutic targets. The integration of Mendelian …
Potential causal association between serum vitamin D levels and intervertebral disc degeneration: A mendelian randomization study
L Liu, C Sun, B Huang, D Zhao, C Xiong, F Xu… - Journal of Orthopaedic …, 2024 - Elsevier
Objectives Intervertebral disc degeneration (IDD) is a prevalent musculoskeletal disorder
with substantial implications for disability and healthcare expenditures. The role of serum …
with substantial implications for disability and healthcare expenditures. The role of serum …
Causal relationships between risk of venous thromboembolism and 18 cancers: a bidirectional Mendelian randomization analysis
N Cornish, P Haycock, H Brenner… - International journal …, 2024 - academic.oup.com
Background People with cancer experience high rates of venous thromboembolism (VTE).
Risk of subsequent cancer is also increased in people experiencing their first VTE. The …
Risk of subsequent cancer is also increased in people experiencing their first VTE. The …
Mendelian randomization does not support serum calcium in prostate cancer risk
J Yarmolinsky, K Berryman, R Langdon… - Cancer Causes & …, 2018 - Springer
Purpose Observational studies suggest that dietary and serum calcium are risk factors for
prostate cancer. However, such studies suffer from residual confounding (due to …
prostate cancer. However, such studies suffer from residual confounding (due to …
[HTML][HTML] The relationship between periodontal disease and gastric cancer: A bidirectional Mendelian randomization study
JC Fan, JH Gan, H Lu - Medicine, 2024 - journals.lww.com
Background: Previous observational studies have suggested a possible association
between periodontal disease and gastric cancer (GC); however, a causal relationship has …
between periodontal disease and gastric cancer (GC); however, a causal relationship has …
Causal relationship between prostate cancer and 12 types of cancers: multivariable and bidirectional Mendelian randomization analyses
X Zhan, T Chen, S Xiong, S Li, X Deng, S Xu… - … Urology and Nephrology, 2024 - Springer
Background Previous observational studies have shown an association between certain
cancers and the subsequent risk of prostate cancer (PCa). However, the causal relationship …
cancers and the subsequent risk of prostate cancer (PCa). However, the causal relationship …