Endothelial dysfunction and platelet hyperactivity in type 2 diabetes mellitus: molecular insights and therapeutic strategies

R Kaur, M Kaur, J Singh - Cardiovascular diabetology, 2018 - Springer
The incidence and prevalence of diabetes mellitus is rapidly increasing worldwide at an
alarming rate. Type 2 diabetes mellitus (T2DM) is the most prevalent form of diabetes …

Platelet activation and prothrombotic mediators at the nexus of inflammation and atherosclerosis: Potential role of antiplatelet agents

R Lordan, A Tsoupras, I Zabetakis - Blood reviews, 2021 - Elsevier
Platelets are central to inflammation-related manifestations of cardiovascular diseases
(CVD) such as atherosclerosis. Platelet-activating factor (PAF), thrombin, thromboxane A 2 …

A comprehensive review of traditional uses, bioactivity potential, and chemical diversity of the genus Gracilaria (Gracilariales, Rhodophyta)

P Torres, JP Santos, F Chow, DYAC dos Santos - Algal Research, 2019 - Elsevier
The genus Gracilaria is an important marine bio-resource since some members are a source
of about 80% of the global production of agar. Moreover, species of Gracilaria are used in …

PI3K inhibitors in thrombosis and cardiovascular disease

TN Durrant, I Hers - Clinical and Translational Medicine, 2020 - Springer
Abstract Phosphoinositide 3-kinases (PI3Ks) are lipid kinases that regulate important
intracellular signalling and vesicle trafficking events via the generation of 3 …

Inhibition of platelet aggregation and thrombosis by indole alkaloids isolated from the edible insect Protaetia brevitarsis seulensis (Kolbe)

JI Lee, W Lee, MA Kim, JS Hwang… - Journal of Cellular …, 2017 - Wiley Online Library
Protaetia brevitarsis seulensis (Kolbe) has been temporarily registered as a food material by
the Ministry of Food and Drug Safety of Korea (MFDS). The current study aimed to discover …

In vitro and in vivo implications of rationally designed bromelain laden core-shell hybrid solid lipid nanoparticles for oral administration in thrombosis management

M Sharma, D Chaudhary - Nanomedicine: Nanotechnology, Biology and …, 2022 - Elsevier
Bromelain, a dietary supplement of cysteine protease family having promising results
against thrombosis, is gaining attention. Yet poor mechanical stability, gastric instability, high …

[HTML][HTML] Endothelial dysfunction, platelet hyperactivity, hypertension, and the metabolic syndrome: molecular insights and combating strategies

D Das, NR Shruthi, A Banerjee, G Jothimani… - Frontiers in …, 2023 - ncbi.nlm.nih.gov
Metabolic syndrome (MetS) is a multifaceted condition that increases the possibility of
developing atherosclerotic cardiovascular disease. MetS includes obesity, hypertension …

Biomarker-based preoperative risk stratification for patients undergoing non-cardiac surgery

T Yurttas, R Hidvegi, M Filipovic - Journal of clinical medicine, 2020 - mdpi.com
Perioperative morbidity and mortality remains a substantial problem and is strongly
associated with patients' cardiac comorbidities. Guidelines for the cardiovascular …

[HTML][HTML] Aspirin Before Elective Surgery—Stop or Continue?: A Single-center Cross-sectional Study

L Plümer, M Seiffert, MA Punke, JF Kersten… - Deutsches Ärzteblatt …, 2017 - ncbi.nlm.nih.gov
Background Cessation of long-term aspirin treatment before noncardiac surgery can cause
adverse cardiac events in patients at risk, particularly in those with previous percutaneous …

Роль тромбоцитов в воспалении и иммунитете

СП Свиридова, ОВ Сомонова, ШР Кашия… - Research'n Practical …, 2018 - cyberleninka.ru
В последние десятилетия достигнут существенный прогресс в понимании механизмов
функционирования тромбоцитов и коррекции тромбоцитарного гемостаза …