EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs: 2016 update

JS Smolen, R Landewé, J Bijlsma… - Annals of the …, 2017 - ard.bmj.com
Recent insights in rheumatoid arthritis (RA) necessitated updating the European League
Against Rheumatism (EULAR) RA management recommendations. A large international …

Rheumatoid arthritis therapy reappraisal: strategies, opportunities and challenges

JS Smolen, D Aletaha - Nature Reviews Rheumatology, 2015 - nature.com
Rheumatoid arthritis (RA) is considered a chronic disease that cannot be cured. Biologic
agents have enabled good therapeutic successes; however, the response to biologic …

Treating rheumatoid arthritis to target: 2014 update of the recommendations of an international task force

JS Smolen, FC Breedveld, GR Burmester… - Annals of the …, 2016 - ard.bmj.com
Background Reaching the therapeutic target of remission or low-disease activity has
improved outcomes in patients with rheumatoid arthritis (RA) significantly. The treat-to-target …

Synovial tissue research: a state-of-the-art review

C Orr, E Vieira-Sousa, DL Boyle, MH Buch… - Nature Reviews …, 2017 - nature.com
The synovium is the major target tissue of inflammatory arthritides such as rheumatoid
arthritis. The study of synovial tissue has advanced considerably throughout the past few …

2010 rheumatoid arthritis classification criteria: an American College of Rheumatology/European League Against Rheumatism collaborative initiative

D Aletaha, T Neogi, AJ Silman, J Funovits… - Arthritis & …, 2010 - Wiley Online Library
Abstract Objective The 1987 American College of Rheumatology (ACR; formerly, the
American Rheumatism Association) classification criteria for rheumatoid arthritis (RA) have …

EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs

JS Smolen, R Landewé, FC Breedveld… - Annals of the …, 2010 - ard.bmj.com
Treatment of rheumatoid arthritis (RA) may differ among rheumatologists and currently, clear
and consensual international recommendations on RA treatment are not available. In this …

Infliximab and methotrexate in the treatment of rheumatoid arthritis

PE Lipsky, DMFM van der Heijde… - … England Journal of …, 2000 - Mass Medical Soc
Background Neutralization of tumor necrosis factor α (TNF-α) for three to six months reduces
the symptoms and signs of rheumatoid arthritis. However, the capacity of this approach to …

Mesenchymal stem cell-based therapy for rheumatoid arthritis

M Sarsenova, A Issabekova, S Abisheva… - International journal of …, 2021 - mdpi.com
Mesenchymal stem cells (MSCs) have great potential to differentiate into various types of
cells, including but not limited to, adipocytes, chondrocytes and osteoblasts. In addition to …

Clinical and radiographic outcomes of four different treatment strategies in patients with early rheumatoid arthritis (the BeSt study): a randomized, controlled trial

YPM Goekoop‐Ruiterman… - Arthritis & …, 2005 - Wiley Online Library
Methods. In a multicenter, randomized clinical trial, 508 patients were allocated to 1 of 4
treatment strategies: sequential disease-modifying antirheumatic drug monotherapy (group …

Therapeutic strategies for rheumatoid arthritis

JS Smolen, G Steiner - Nature reviews Drug discovery, 2003 - nature.com
Recent years have seen considerable advances in our understanding of both the clinical
and basic-research aspects of rheumatoid arthritis. Clinical progress has come from a better …