Hemodialysis, the most common modality of renal replacement therapy, is critically required
to remove uremic toxins from the blood of patients with end-stage kidney disease. However …

Acute renal failure (ARF) in critically ill patients is currently very frequent and requires renal
replacement therapy (RRT) in many patients. During the last 15 years, several studies have …

End-stage renal disease (ESRD) patients on chronic hemodialysis have repeated blood
exposure to artificial surfaces that can trigger clot formation within the hemodialysis circuit …

Heparin is used to prevent clotting during hemodialysis, but heparin-free hemodialysis is
sometimes needed to decrease the risk of bleeding. The HepZero study is a randomized …

Prevention of clotting in the extracorporeal circuit was one of the major hurdles that had to
be overcome to enable the expansion of routine outpatient hemodialysis to free-standing …

Systemic anticoagulation in maintenance hemodialysis (HD) has historically been
considered necessary to maintain the extracorporeal circuit (ECC) and preserve dialysis …

Appropriate anticoagulation for hemodialysis (HD) requires a subtle balance between under‐
and over‐heparinization to prevent extracorporeal circuit (ECC) clotting and bleeding …

The goal of the current study is to enhance the hemocompatibility of polyethersulfone (PES)
membranes using heparin immobilization. Heparin was immobilized covalently and via …

Unfractionated heparin (UFH) is the anticoagulant of choice for most maintenance
hemodialysis units in the United States. Low molecular weight heparin (LMWH) is the norm …

Hemodialysis is a life-sustaining therapy for millions of people worldwide. However, despite
considerable technical and scientific improvements, results are still not fully satisfactory in …