Anticancer potential of azole containing marine natural products: current and future perspectives

D Rani, V Garg, R Dutt - Anti-Cancer Agents in Medicinal …, 2021 - ingentaconnect.com
Background: Despite significant advancement in oncology research, cancer still poses one
of the leading causes of mortality worldwide. The increased incidences of cancer may be …

Flavonoids and PI3K/Akt/mTOR signaling cascade: a potential crosstalk in anticancer treatment

M Suhail, MS Khan, A Ahmad… - Current Medicinal …, 2021 - ingentaconnect.com
Cancer is one of the leading causes of death worldwide. A slight decline in mortality has
been noted, but the currently available treatment options did not give an expected outcome …

[HTML][HTML] Comparative efficacy of epigallocatechin gallate and its nano-formulation in prostate cancer 3D spheroids model

RF Alserihi, MRS Mohammed, M Kaleem… - Journal of King Saud …, 2023 - Elsevier
Abstract Background Prostate cancer (PCa) remains one of the clinically relevant
pathologies that needs pragmatic and effective treatment approaches. The current study …

Recent advances in natural therapeutic approaches for the treatment of cancer

XJ Wang, JY Chen, LQ Fu, MJ Yan - Journal of Chemotherapy, 2020 - Taylor & Francis
Plants and natural compounds have been widely recognized to have potential for the
prevention of cancer progression and as complementary or standalone treatments for …

Anticancer potential of gold nanoparticles (AuNPs) using a battery of in vitro tests

NO Alafaleq, A Alomari, MS Khan, GM Shaik… - Nanotechnology …, 2022 - degruyter.com
This study synthesized gold nanoparticles (AuNPs) using a facile microwave-assisted
chemical route and evaluated them as potential anticancer candidates against breast and …

Synthesis and anticancer properties of 'azole'based chemotherapeutics as emerging chemical moieties: A comprehensive review

P Prasher, M Sharma, F Zacconi… - Current Organic …, 2021 - ingentaconnect.com
Azole frameworks serve as privileged scaffolds in the contemporary drug design paradigm
owing to their unique physicochemical profile that promotes the development of highly …

Alkaloids of Peganum harmala: Anticancer biomarkers with promising outcomes

A Jalali, F Dabaghian… - Current pharmaceutical …, 2021 - ingentaconnect.com
Background: Cancer is a serious and growing global health issue worldwide. In the
cancerous cells, the normal cell cycle has been disrupted via a series of irreversible …

Anticancer potential of cardiac glycosides and steroid-azole hybrids

Y Hou, C Shang, T Meng, W Lou - Steroids, 2021 - Elsevier
Steriods are well-known scaffolds that have a widespread occurrence in different
compounds characterized by extensive biological properties including anticancer activity …

Dietary phenolic acids and flavonoids as potential anti-cancer agents: current state of the art and future perspectives

RK Bonta - Anti-Cancer Agents in Medicinal Chemistry …, 2020 - ingentaconnect.com
Background: Cancer is a rapidly growing disease and the second most leading cause of
death worldwide. Breast, colon, lung, and prostate cancer are the most diagnosed types of …

Azole-methyl-3-(4-phenoxyphenyl) quinazolin-4 (3H) ones, novel quinazoline-azole hybrid scaffolds, as new potent anticancer agents: Design, synthesis, biological …

SZ Gheshlaghi, A Ebrahimi, Z Faghih, Z Faghih… - Tetrahedron, 2023 - Elsevier
Herein we describe design and synthesis of new series of small quinazoline molecule
connected to the azole moieties. Molecular docking screening were conducted on 102 …