Objective To evaluate the underlying pharmacology safety, and misuse/abuse of
transdermal fentanyl, one of the cornerstone pharmacotherapies for patients with chronic …

Fentanyl is a synthetic opioid with short-acting analgesic activity after intravenous or
subcutaneous administration. The low molecular weight, high potency and lipid solubility of …

This book presents 55 clinical cases emphasizing the basic science aspects of pathology
and is “the closest you can get to the wards without seeing patients.” Each case includes an …

Tony L. Yaksh and Mark S. Wallace well-versed in the uses of opium; Arab traders
introduced the drug to the Orient, where it was employed mainly for the control of dysentery …

Written for practitioners in the field, this critically acclaimed bestseller provides authoritative
information focused on the investigation of drug-related deaths and practical approaches to …

Introduction The illicit opioid supply in the US is increasingly adulterated with fentanyl. As
such, persons with opioid use disorder (OUD) may be regularly exposed to fentanyl …

Transdermal delivery allows continuous systemic application of opioids through the intact
skin. This review analyses the pharmacokinetic properties of transdermal opioid …

Fentanyl is a synthetic, highly selective opioid with many desirable physicochemical
properties, including a high lipophilicity and predictable pharmacokinetics. These properties …

Fentanyl is a synthetic opioid agonist which interacts primarily with the μ-opioid receptor.
The low molecular weight, high potency and lipid solubility of fentanyl make it suitable for …

Direct conversion from oral morphine to transdermal fentanyl with a ratio of oral
morphine/transdermal fentanyl (100: 1 mg) daily was examined in patients with cancer pain …