The prefrontal cortex plays a central role in the control of complex cognitive processes
including action control and decision making. It also shows a specific pattern of delayed …

Insulin crosses the blood–brain barrier to enter the brain from the periphery. In the brain,
insulin has well-established actions in the hypothalamus, as well as at the level of …

Introduction Obesity is associated with elevated endocannabinoid tone, gut dysbiosis, and
inflammation predisposing to diabetes. The endocannabinoid system mediates the effects of …

Physical activity leads to well-established health benefits. Current efforts to enhance
physical activity have targeted mainly socioeconomic factors. However, despite these efforts …

Dopamine has long been implicated as a critical neural substrate mediating anorexia
nervosa (AN). Despite nearly 50 years of research, the putative direction of change in …

Purpose Individuals with vitamin D (VD) insufficiency have a greater tendency to develop
obesity and have increased systemic inflammation. Gut microbiota are involved in the …

Different types of rewards such as food and money can similarly drive our behavior owing to
shared brain processes encoding their subjective value. However, while the value of money …

Insulin receptors are expressed throughout the adult brain, and insulin from the periphery
reaches the central nervous system. In humans and rodents, actions of insulin in the brain …

Rationale The endocannabinoid system makes critical contributions to reward processing,
motivation, and behavioral control. Repeated exposure to THC or other cannabinoid drugs …

The CB2 cannabinoid receptor has been found in brain areas that are part of the reward
system and has been shown to play a role in food intake regulation. Herein, we conducted a …