Reactive oxygen species, toxicity, oxidative stress, and antioxidants: Chronic diseases and aging

K Jomova, R Raptova, SY Alomar, SH Alwasel… - Archives of …, 2023 - Springer
A physiological level of oxygen/nitrogen free radicals and non-radical reactive species
(collectively known as ROS/RNS) is termed oxidative eustress or “good stress” and is …

Health benefits of quercetin in age-related diseases

Deepika, PK Maurya - Molecules, 2022 - mdpi.com
Polyphenols are the known group of phytochemicals that essentially consists of phenolic
rings. These are the plant product present in varied fruits and vegetables. These secondary …

[HTML][HTML] Oxidative stress and inflammation in osteoarthritis pathogenesis: Role of polyphenols

MY Ansari, N Ahmad, TM Haqqi - Biomedicine & pharmacotherapy, 2020 - Elsevier
Osteoarthritis (OA) is the most prevalent joint degenerative disease leading to irreversible
structural and functional changes in the joint and is a major cause of disability and reduced …

Pathological mechanisms and therapeutic strategies for Alzheimer's disease

Y Ju, KY Tam - Neural Regeneration Research, 2022 - journals.lww.com
Alzheimer's disease is a rather complex neurodegenerative disease, which is attributed to a
combination of multiple factors. Among the many pathological pathways, synaptic …

Gut microbiota and dysbiosis in Alzheimer's disease: implications for pathogenesis and treatment

S Liu, J Gao, M Zhu, K Liu, HL Zhang - Molecular neurobiology, 2020 - Springer
Understanding how gut flora influences gut-brain communications has been the subject of
significant research over the past decade. The broadening of the term “microbiota-gut-brain …

Dietary polyphenols: Regulate the advanced glycation end products-RAGE axis and the microbiota-gut-brain axis to prevent neurodegenerative diseases

Y Li, Y Peng, Y Shen, Y Zhang, L Liu… - Critical Reviews in Food …, 2023 - Taylor & Francis
Advanced glycation end products (AGEs) are formed in non-enzymatic reaction, oxidation,
rearrangement and cross-linking between the active carbonyl groups of reducing sugars …

Use of Alcalase in the production of bioactive peptides: A review

VG Tacias-Pascacio, R Morellon-Sterling… - International journal of …, 2020 - Elsevier
This review aims to cover the uses of the commercially available protease Alcalase in the
production of biologically active peptides since 2010. Immobilization of Alcalase has also …

Effect of physical activity/exercise on oxidative stress and inflammation in muscle and vascular aging

M El Assar, A Álvarez-Bustos, P Sosa, J Angulo… - International Journal of …, 2022 - mdpi.com
Functional status is considered the main determinant of healthy aging. Impairment in
skeletal muscle and the cardiovascular system, two interrelated systems, results in …

Severe Glutathione Deficiency, Oxidative Stress and Oxidant Damage in Adults Hospitalized with COVID-19: Implications for GlyNAC (Glycine and N-Acetylcysteine) …

P Kumar, O Osahon, DB Vides, N Hanania, CG Minard… - Antioxidants, 2021 - mdpi.com
Humanity is battling a respiratory pandemic pneumonia named COVID-19 which has
resulted in millions of hospitalizations and deaths. COVID-19 exacerbations occur in waves …

[HTML][HTML] Metformin in aging and aging-related diseases: clinical applications and relevant mechanisms

S Chen, D Gan, S Lin, Y Zhong, M Chen, X Zou… - Theranostics, 2022 - ncbi.nlm.nih.gov
Aging is a natural process, which plays a critical role in the pathogenesis of a variety of
diseases, ie, aging-related diseases, such as diabetes, osteoarthritis, Alzheimer disease …