The enteric nervous system (ENS) is the largest division of the peripheral nervous system
and closely resembles components and functions of the central nervous system. Although …

Multidirectional interactions between the nervous and immune systems have been
documented in homeostasis and pathologies ranging from multiple sclerosis to autism, and …

We read with interest the article by de Jong and colleagues (Gut 2003; 52: 547–51)
reporting studies of genetic associations between DNA polymorphisms in xenobiotic …

The monolayer of columnar epithelial cells lining the gastrointestinal tract—the intestinal
epithelial barrier (IEB)—is the largest exchange surface between the body and the external …

Background and aims: The incidence of irritable bowel syndrome (IBS) or functional bowel
disorders (FBD) after bacillary dysentery (BD) has not been extensively evaluated, and little …

Background & Aims: A variety of gastrointestinal motility disorders have been attributed to
alterations of interstitial cells of Cajal and malformations of the enteric nervous system. This …

Gastrointestinal dysfunction is a prominent non-motor feature of Parkinson's disease (PD)
that contributes directly to the morbidity of patients, complicates management of motor …

It is well known that tumours arising in different organs are innervated and that 'perineural
invasion'(cancer cells escaping from the tumour by following the nerve trunk) is a negative …

The enteric nervous system is composed of both neurons and glia. Recent evidence
indicates that enteric glia–which vastly outnumber enteric neurons–are actively involved in …

BACKGROUND & AIMS: Enteric nervous system stem cells (ENSSCs) provide potential
therapeutic tools to replenish absent ganglia in Hirschsprung's disease. Although full …