Numerous harmful factors that affect the human body from birth to old age cause many
disturbances, eg, in the structure of the genome, inducing cell apoptosis and their …

Recent progress in protein-based nanomedicine, inspired by the success of Abraxane®
albumin-paclitaxel nanoparticles, have resulted in novel therapeutics used for treatment of …

Iron dyshomeostasis can cause neuronal damage to iron-sensitive brain regions.
Neurodegeneration with brain iron accumulation reflects a group of disorders caused by iron …

Lactoferrin (Lf), a cationic glycoprotein able to chelate two ferric irons per molecule, is
synthesized by exocrine glands and neutrophils. Since the first anti-microbial function …

Parkinson's disease is a common progressive and multifactorial neurodegenerative disease,
characterized by the loss of midbrain dopaminergic neurons. Numerous pathological …

Alzheimer's disease (AD), considered the most common type of dementia, is characterized
by a progressive loss of memory, visuospatial, language and complex cognitive abilities. In …

Neurodegeneration is a highly complex process which is associated with a variety of
molecular mechanisms related to ageing. Among neurodegenerative disorders, Alzheimer's …

Background Evidences of infectious pathogens in Alzheimer's disease (AD) brains may
suggest a deteriorated innate immune system in AD pathophysiology. We previously …

Alzheimer's disease (AD) is the most prevalent cause of dementia, accounting for
approximately 60%–80% of all cases. Although much effort has been made over the years …

Inflammatory bowel disease (IBD), encompassing ulcerative colitis (UC) and Crohn's
disease (CD), is one of the main types of intestinal inflammatory diseases with intestine …