[HTML][HTML] Pseudomonas aeruginosa: pathogenesis, virulence factors, antibiotic resistance, interaction with host, technology advances and emerging therapeutics
Pseudomonas aeruginosa (P. aeruginosa) is a Gram-negative opportunistic pathogen that
infects patients with cystic fibrosis, burn wounds, immunodeficiency, chronic obstructive …
infects patients with cystic fibrosis, burn wounds, immunodeficiency, chronic obstructive …
[HTML][HTML] CRISPR-based diagnostics
MM Kaminski, OO Abudayyeh, JS Gootenberg… - Nature Biomedical …, 2021 - nature.com
The accurate and timely diagnosis of disease is a prerequisite for efficient therapeutic
intervention and epidemiological surveillance. Diagnostics based on the detection of nucleic …
intervention and epidemiological surveillance. Diagnostics based on the detection of nucleic …
Bacterial defences: mechanisms, evolution and antimicrobial resistance
Throughout their evolutionary history, bacteria have faced diverse threats from other
microorganisms, including competing bacteria, bacteriophages and predators. In response …
microorganisms, including competing bacteria, bacteriophages and predators. In response …
[HTML][HTML] Biofilms as promoters of bacterial antibiotic resistance and tolerance
C Uruén, G Chopo-Escuin, J Tommassen… - Antibiotics, 2020 - mdpi.com
Multidrug resistant bacteria are a global threat for human and animal health. However, they
are only part of the problem of antibiotic failure. Another bacterial strategy that contributes to …
are only part of the problem of antibiotic failure. Another bacterial strategy that contributes to …
Beyond horizontal gene transfer: the role of plasmids in bacterial evolution
J Rodríguez-Beltrán, J DelaFuente… - Nature Reviews …, 2021 - nature.com
Plasmids have a key role in bacterial ecology and evolution because they mobilize
accessory genes by horizontal gene transfer. However, recent studies have revealed that …
accessory genes by horizontal gene transfer. However, recent studies have revealed that …
Clinically relevant mutations in core metabolic genes confer antibiotic resistance
Although metabolism plays an active role in antibiotic lethality, antibiotic resistance is
generally associated with drug target modification, enzymatic inactivation, and/or transport …
generally associated with drug target modification, enzymatic inactivation, and/or transport …
Understanding human health risks caused by antibiotic resistant bacteria (ARB) and antibiotic resistance genes (ARG) in water environments: Current knowledge and …
Aquatic environments are identified as an ideal setting for acquisition and dissemination of
antibiotic resistance, and human exposure to antibiotic resistant bacteria (ARB) and …
antibiotic resistance, and human exposure to antibiotic resistant bacteria (ARB) and …
Importance of antibiotic residues in animal food
Veterinary medicines, especially antibiotics, are among the most important components
related to animal feed production. Generally, the main use of antibiotics in animals is for the …
related to animal feed production. Generally, the main use of antibiotics in animals is for the …
[HTML][HTML] Structure, genetics and worldwide spread of New Delhi metallo-β-lactamase (NDM): a threat to public health
Background The emergence of carbapenemase producing bacteria, especially New Delhi
metallo-β-lactamase (NDM-1) and its variants, worldwide, has raised amajor public health …
metallo-β-lactamase (NDM-1) and its variants, worldwide, has raised amajor public health …
Both silver ions and silver nanoparticles facilitate the horizontal transfer of plasmid-mediated antibiotic resistance genes
Antibiotic resistance in bacteria is a growing threat to global human health. Horizontal gene
transfer (HGT) of antibiotic resistance genes (ARGs) is recognized as the primary contributor …
transfer (HGT) of antibiotic resistance genes (ARGs) is recognized as the primary contributor …