Articular cartilage shows limited self-healing ability owing to its low cellularity and
avascularity. Untreated cartilage defects display an increased propensity to degenerate …

Infrapatellar fat pad–derived mesenchymal stem cells (IPFP-MSCs) are a type of adipose-
derived stem cell (ADSC). They potentially contribute to cartilage regeneration and …

Mesenchymal stem cells (MSCs) therapy shows the potential benefits to relieve clinical
symptoms of osteoarthritis (OA), but it is uncertain if it can repair articular cartilage lesions …

Background Bioactive materials have now raised considerable attention for the treatment of
osteoarthritis (OA), such as knee OA, rheumatoid OA, and temporomandibular joint (TMJ) …

Osteoarthritis (OA) is a common degenerative joint disorder that affects joint function,
mobility, and pain. The release of proinflammatory cytokines stimulates matrix …

The design of a scaffold that can regulate the sequential differentiation of bone marrow
mesenchymal stromal cells (BMSCs) according to the endochondral ossification (ECO) …

Current clinical strategies for restoring cartilage defects do not adequately consider taking
the necessary steps to prevent the formation of hypertrophic tissue at injury sites …

Alzheimer's disease (AD) and osteoarthritis (OA) are both senile degenerative diseases.
Clinical studies have found that OA patients have a significantly increased risk of AD in their …

Articular cartilage allows the human body to buffer and absorb stress during normal
exercise. It is mainly composed of cartilage cells and the extracellular matrix and is …

Bone growth occurs in the epiphyseal growth plate (EGP) and epiphyseal growth plate cells
(EGPCs) exist in EGP. EGPCs, including skeletal stem cells (SSCs), are cells that induce …