[HTML][HTML] Research progress in arthritis treatment with the active components of Herba siegesbeckiae

X Lv, X Wang, X Wang, Y Han, H Chen, Y Hao… - Biomedicine & …, 2023 - Elsevier
Arthritis is a group of diseases characterized by joint pain, swelling, stiffness, and limited
movement. Osteoarthritis, rheumatoid arthritis, and gouty arthritis are the most common …

The chromatin landscape of pathogenic transcriptional cell states in rheumatoid arthritis

K Weinand, S Sakaue, A Nathan, AH Jonsson… - Nature …, 2024 - nature.com
Synovial tissue inflammation is a hallmark of rheumatoid arthritis (RA). Recent work has
identified prominent pathogenic cell states in inflamed RA synovial tissue, such as T …

Transcription factors in the development and treatment of immune disorders

SD Patalano, P Fuxman Bass, JI Fuxman Bass - Transcription, 2023 - Taylor & Francis
Immune function is highly controlled at the transcriptional level by the binding of transcription
factors (TFs) to promoter and enhancer elements. Several TF families play major roles in …

Curcumin Co-Encapsulation Potentiates Anti-Arthritic Efficacy of Meloxicam Biodegradable Nanoparticles in Adjuvant-Induced Arthritis Animal Model

B Aslam, A Hussain, MN Faisal, ZD Sindhu, RU Khan… - Biomedicines, 2023 - mdpi.com
This study aimed to evaluate the anti-arthritic activity of curcumin and meloxicam co-loaded
PLGA nanoparticles in adjuvant-induced arthritic rats. PLGA nanoparticles encapsulating …

[HTML][HTML] Exploring the therapeutic potential of regulatory T cell in rheumatoid arthritis: Insights into subsets, markers, and signaling pathways

QY Su, HC Li, XJ Jiang, ZQ Jiang, Y Zhang… - Biomedicine & …, 2024 - Elsevier
Rheumatoid arthritis (RA) is a complex autoimmune inflammatory rheumatic disease
characterized by an imbalance between immunological reactivity and immune tolerance …

Unveiling the Nexus: Cellular Metabolomics Unravels the Impact of Estrogen on Nicotinamide Metabolism in Mitigating Rheumatoid Arthritis Pathogenesis

S Malik, D Chakraborty, P Agnihotri, V Kumar, S Biswas - Metabolites, 2024 - mdpi.com
Rheumatoid arthritis (RA) is a metabolic joint disorder influenced by hormonal regulation,
notably estrogen, which plays a cytoprotective role against inflammation. While estrogen's …

Repeated LPS induces training and tolerance of microglial responses across brain regions

J Kim, O Sullivan, K Lee, J Jao, J Tamayo, AM Madany… - bioRxiv, 2024 - biorxiv.org
Background: Neuroinflammation is involved in the pathogenesis of almost every central
nervous system disorder. As the brain's innate immune cells, microglia fine tune their activity …

[引用][C] DNA Damage and Cellular Senescence in Osteoarthritis: An Unexpected Role for Interferon Regulatory Factor 1 in Chondrocyte DNA Repair.

BO Diekman, RF Loeser - Arthritis & Rheumatology (Hoboken, NJ), 2024 - europepmc.org
DNA Damage and Cellular Senescence in Osteoarthritis: An Unexpected Role for Interferon
Regulatory Factor 1 in Chondrocyte DNA Repair. - Abstract - Europe PMC Sign in | Create an …