Prevalence of polypharmacy and risks of potentially inappropriate medication use in the older population in a developing country: a systematic review and meta …

AS Bhagavathula, EA Gebreyohannes, D Fialova - Gerontology, 2022 - karger.com
Abstract Background and Aim: Polypharmacy and potentially inappropriate medication (PIM)
use in older populations (65+ years) have not yet been investigated by meta-analyses in …

Age-related changes in hepatic function: an update on implications for drug therapy

JL Tan, JG Eastment, A Poudel, RE Hubbard - Drugs & aging, 2015 - Springer
The accumulation of deficits with increasing age results in a decline in the functional
capacity of multiple organs and systems. These changes can have a significant influence on …

[HTML][HTML] Polypharmacy—an upward trend with unpredictable effects

D Moßhammer, H Haumann, K Mörike… - Deutsches Ärzteblatt …, 2016 - ncbi.nlm.nih.gov
Background Guideline-oriented treatments can lead to polypharmacy, ie, the simultaneous
long-term use of multiple drugs. Polypharmacy mainly affects elderly patients. The goal of …

Chronic polypharmacy with increasing drug burden index exacerbates frailty and impairs physical function, with effects attenuated by deprescribing, in aged mice

J Mach, G Gemikonakli, C Logan… - The Journals of …, 2021 - academic.oup.com
Polypharmacy (use of≥ 5 medications) and increasing Drug Burden Index (DBI) score
(measure of person's total exposure to anticholinergic/sedative medications) are associated …

Deprescribing medications for older adults in the primary care context: a mixed studies review

RJ Gillespie, L Harrison, J Mullan - Health science reports, 2018 - Wiley Online Library
Aims This review investigates the factors that influence deprescribing of medications in
primary care from the perspective of general practitioners (GPs) and community‐living older …

Barriers and enablers to deprescribing in people with a life-limiting disease: a systematic review

K Paque, R Vander Stichele, M Elseviers… - Palliative …, 2019 - journals.sagepub.com
Background: Knowing the barriers/enablers to deprescribing in people with a life-limiting
disease is crucial for the development of successful deprescribing interventions. These …

How willing are patients or their caregivers to deprescribe: a systematic review and meta-analysis

YL Chock, YL Wee, SL Gan, KW Teoh, KY Ng… - Journal of general …, 2021 - Springer
Background Polypharmacy is associated with the increased use of potentially inappropriate
medications, where the risks of medicine use outweigh its benefits. Stopping medicines …

Guidance to manage inappropriate polypharmacy in older people: systematic review and future developments

D Stewart, A Mair, M Wilson, P Kardas… - Expert opinion on …, 2017 - Taylor & Francis
Introduction: Single disease state led evidence-based guidelines do not provide sufficient
coverage of issues of multimorbidities, with the cumulative impact of recommendations often …

国际护士理事会2021 年《 护士处方权指南》 解读.

张倩, 李明子, 韩世范, 李湘萍, 朱瑞芳… - Chinese Nursing …, 2022 - search.ebscohost.com
摘要处方权是传统护理执业范畴扩展的标志, 也是高级实践护士有别于一般注册护士的特征性
权限, 目前全球已有70 余个国家及地区发展高级实践护士角色, 44 个国家或地区立法规定护士 …

Emerging approaches to polypharmacy among older adults

RS Mehta, BD Kochar, K Kennelty, ME Ernst, AT Chan - Nature Aging, 2021 - nature.com
Polypharmacy is a major health issue for older adults. Entangled with several geriatric
syndromes, including frailty, falls and cognitive decline, research focused on polypharmacy …