Inflammatory mediators in the pathogenesis of periodontitis

T Yucel-Lindberg, T Båge - Expert reviews in molecular medicine, 2013 - cambridge.org
Periodontitis is a chronic inflammatory condition of the periodontium involving interactions
between bacterial products, numerous cell populations and inflammatory mediators. It is …

[HTML][HTML] Is inflammation a friend or foe for orthodontic treatment?: Inflammation in orthodontically induced inflammatory root resorption and accelerating tooth …

M Yamaguchi, S Fukasawa - International journal of molecular sciences, 2021 - mdpi.com
The aim of this paper is to provide a review on the role of inflammation in orthodontically
induced inflammatory root resorption (OIIRR) and accelerating orthodontic tooth movement …

Review of osteoimmunology and the host response in endodontic and periodontal lesions

DT Graves, T Oates, GP Garlet - Journal of oral microbiology, 2011 - Taylor & Francis
Both lesions of endodontic origin and periodontal diseases involve the host response to
bacteria and the formation of osteolytic lesions. Important for both is the upregulation of …

IL-1 and TNF antagonists inhibit the inflammatory response and bone loss in experimental periodontitis

R Assuma, T Oates, D Cochran, S Amar… - The Journal of …, 1998 - journals.aai.org
Periodontal disease is the most frequent cause of tooth loss in humans and is the most
prevalent disease associated with bone loss, including osteoporosis. Periodontal …

Differentiation of monocytes to macrophages primes cells for lipopolysaccharide stimulation via accumulation of cytoplasmic nuclear factor κB

S Takashiba, TE Van Dyke, S Amar… - Infection and …, 1999 - Am Soc Microbiol
During infection, circulating blood monocytes migrate from the vasculature to the
extravascular compartments where they mature into tissue macrophages. The maturation …

Salivary biomarkers of existing periodontal disease: a cross-sectional study

CS Miller, CP King Jr, MC Langub, RJ Kryscio… - The Journal of the …, 2006 - Elsevier
Background The authors conducted a study to determine if salivary biomarkers specific for
three aspects of periodontitis—inflammation, collagen degradation and bone turnover …

Relationship between clinical parameters and cytokine profiles in inflamed gingival tissue and serum samples from patients with chronic periodontitis

R Górska, H Gregorek, J Kowalski… - Journal of clinical …, 2003 - Wiley Online Library
Objective: The purpose of the present study was to assess the relation between clinical
parameters and concentrations of the key (IL‐1β, TNF‐α, IL‐2, IFN‐γ, IL‐4, IL‐10) cytokines …

[HTML][HTML] Blockade of RAGE suppresses periodontitis-associated bone loss in diabetic mice

E Lalla, IB Lamster, M Feit, L Huang… - The Journal of …, 2000 - Am Soc Clin Investig
Diabetes is associated with increased prevalence, severity, and progression of periodontal
disease. To test the hypothesis that activation of RAGE (Receptor for Advanced Glycation …

Identification of genetic risk factors for periodontitis and possible mechanisms of action

BG Loos, RP John, ML Laine - Journal of clinical …, 2005 - Wiley Online Library
Aim: To review the literature for genetic risk factors associated with periodontitis. Methods:
Computerized search of the literature in English using key words: Periodontitis; Genes; …

Macrophage polarization in human gingival tissue in response to periodontal disease

LN Zhou, CS Bi, LN Gao, Y An, F Chen… - Oral diseases, 2019 - Wiley Online Library
Objective Although accumulating evidence indicates that macrophages are central players
in the destructive and reparative phases of periodontal disease, their polarization states at …