Vitamin D is a hormone with both genomic and non-genomic actions. It exerts its activity by
binding vitamin D receptor (VDR), which belongs to the superfamily of nuclear receptors and …

During the last years, studies investigating the intriguing association between
immunodeficiency and autoimmunity led to the discovery of new monogenic disorders, the …

Background The role of the immune system and inflammatory response in the pathogenesis
of the severe manifestations of coronavirus disease 2019 (COVID-19) is well known …

Nutraceuticals, including vitamin D, vitamin A, zinc, lactoferrin, polyphenols coenzyme Q,
magnesium, and selenium, are implicated in the modulation of the complex molecular …

Dendritic cells (DCs) are crucial cells for initiating and maintaining immune response. They
play critical role in homeostasis, inflammation, and autoimmunity. A number of molecules …

Chromosome 22q11. 2 deletion syndrome (22q11. 2DS) is a primary immunodeficiency
characterized by a broad and heterogeneous clinical presentation associated with various …

The clinical expression of 22q11. 2 deletion syndrome (22q11. 2 DS) is extremely variable,
as patients can present with recurrent or severe infections, immune dysregulation, atopic …

El síndrome de deleción 22q11 es la microdeleción cromosómica más frecuente, con una
prevalencia de 1 en 3 a 6000 nacidos vivos. Se presentarán dos casos femeninos …

Congenital heart defects (CHD) are the most common developmental abnormalities,
affecting approximately 0.9% of livebirths. Genetic factors, including copy number variations …

Amaç: Bu çalışmada; kromozom 22q11. 2 Delesyon Sendromu (22q11. 2DS) tanısı konulan
hastaların, genetik polikliniğine başvuru nedenleri ile birlikte, klinik ve laboratuvar …