The reconstruction and repair of large bone defects, resulting from trauma, cancer or
metabolic disorders, is a major clinical challenge in orthopaedics. Clinically available …

The research on ceramic scaffolds for bone tissue engineering is, nowadays, one of the
newest and most attractive topics in the field of materials for biomedical applications. These …

Because tissues are characterized by a well-defined three-dimensional arrangement of
cells, tissue engineering scaffolds that facilitate the organization and differentiation of new …

Bone marrow‑derived mesenchymal stem cells (BMSCs) have the potential to form a variety
of mesenchymal tissue types, which are a source of cells for bone tissue engineering …

Calcium phosphate ceramics have been widely used for filling bone defects to aid in the
regeneration of new bone tissue. Addition of osteogenic cells to porous ceramic scaffolds …

Regenerative medicine has rapidly evolved over the past decade owing to its potential
applications to improve human health. Targeted differentiations of stem cells promise to …

Three types of poorly crystallized calcium-deficient hydroxyapatites (CDHA) with Ca/P molar
ratios 1.50, 1.58, and 1.67 were prepared from CaHPO4⊙ 2H2O and KOH. These were …

The field of tissue engineering integrates the latest advances in molecular biology,
biochemistry, engineering, material science, and medical transplantation. Researchers in …

OBJECTIVE: To compare mandibular bone regeneration with bone morphogenetic protein‐
2 (BMP‐2) delivered with two carriers: a hyaluronic acid polymer (HY), and a collagen …

Mesenchymal stem/stromal cells (MSC) are rapidly becoming a leading candidate for use in
tissue regeneration, with first generation of therapies being approved for use in orthopaedic …