Simple Summary Lung cancer is very difficult to cure, especially when it has spread to other
parts of the body. One of the main reasons that delay the identification of effective therapies …

Lung cancer is one of the most aggressive and deadliest health threats. There has been an
increasing interest in non-coding RNA (ncRNA) recently, especially in the areas of …

Purpose Non-small cell lung cancer (NSCLC) is among the leading causes of morbidity and
mortality worldwide. Despite the availability of several treatment options, the five-year …

Despite the progress in the comprehension of LC progression, risk, immunologic control,
and treatment choices, it is still the primary cause of cancer-related death. LC cells possess …

Fish liver cell lines are valuable tools to understand the toxicity of chemicals in aquatic
vertebrates. While conventional 2D cell cultures grown in monolayers are well established …

Multicellular 3D tumor models are becoming a powerful tool for testing of novel drug
products and personalized anticancer therapy. Tumor spheroids, a commonly used 3D …

Cancer cells harbor many genetic mutations and gene expression profiles different from
normal cells. Patient-derived cancer cells (PDCC) are preferred materials in cancer study …

Simple Summary Limited knowledge about NSCLC evolution has affected therapeutic
strategies for many decades. The application of NGS-based techniques to studies on ITH …

Pancreatic cancer is a highly malignant and metastatic cancer. Pancreatic cancer can lead
to liver metastases, gallbladder metastases, and duodenum metastases. The identification of …

The study proposes a platform for the formation and culture of non-small cell lung cancer
(NSCLC) spheroids, to obtain an in vitro model suitable for drug and therapy testing. To …