Virtually every eukaryotic cell has an endogenous circadian clock and a biological sex.
These cell-based clocks have been conceptualized as oscillators whose phase can be reset …

A hypothalamic neuropeptide, gonadotropin-releasing hormone (GnRH), is the primary
factor regulating gonadotropin secretion. An inhibitory hypothalamic neuropeptide for …

In seasonal mammals, a distinct photoneuroendocrine circuit that involves the pineal
hormone melatonin tightly synchronizes reproduction with seasons. In the Syrian hamster, a …

A neuropeptide that directly inhibits gonadotropin secretion from the pituitary was
discovered in quail and named gonadotropin-inhibitory hormone (GnIH). The presence and …

Gonadotropin-inhibitory hormone (GnIH) is a novel hypothalamic neuropeptide that was
discovered in quail as an inhibitory factor for gonadotropin release. GnIH inhibits …

Adiponectin is secreted by the adipose tissue and is downregulated in states of obesity and
insulin resistance. There is a growing body of evidence indicating that adiponectin has …

In mammals, melatonin is the pivotal messenger synchronizing biological functions, notably
reproductive activity, with annual daylength changes. Recently, two major findings clarified …

Gonadotropin-inhibitory hormone (GnIH) inhibits gonadotropin release in birds and
mammals. To investigate its role in teleosts, we examined the effects of synthetic goldfish (g) …

LPXRFamide (LPXRFa) peptides have been characterized for their ability to inhibit
gonadotropin (GTH) release in birds and stimulate growth hormone (GH) release in frogs …

Female reproduction requires the precise temporal organization of interacting, estradiol-
sensitive neural circuits that converge to optimally drive hypothalamo-pituitary–gonadal …