Traditional herbal medicine and nanomedicine: Converging disciplines to improve therapeutic efficacy and human health

J Zhang, K Hu, L Di, P Wang, Z Liu, J Zhang… - Advanced drug delivery …, 2021 - Elsevier
Traditional herbal medicine (THM), an ancient science, is a gift from nature. For thousands of
years, it has helped humans fight diseases and protect life, health, and reproduction …

Novel drug delivery systems for loading of natural plant extracts and their biomedical applications

HS Rahman, HH Othman, NI Hammadi… - International journal …, 2020 - Taylor & Francis
Many types of research have distinctly addressed the efficacy of natural plant metabolites
used for human consumption both in cell culture and preclinical animal model systems …

Targeting Akt/CREB/BDNF signaling pathway by ginsenosides in neurodegenerative diseases: A mechanistic approach

SN Zarneshan, S Fakhri, H Khan - Pharmacological research, 2022 - Elsevier
Neurodegenerative diseases (NDDs) are leading causes of death and morbidity in the
elderly worldwide. From the mechanistic/pathological view, oxidative stress, inflammation …

[HTML][HTML] Nanotechnology: an effective tool for enhancing bioavailability and bioactivity of phytomedicine

T Gunasekaran, T Haile, T Nigusse… - Asian Pacific journal of …, 2014 - Elsevier
To achieve the desired therapeutic objective, the drug product must deliver the active drug at
an optimal rate and amount. By proper biopharmaceutic design, the rate and extent of drug …

[HTML][HTML] Notoginsenoside R1-loaded mesoporous silica nanoparticles targeting the site of injury through inflammatory cells improves heart repair after myocardial …

H Li, J Zhu, Y Xu, F Mou, X Shan, Q Wang, B Liu… - Redox Biology, 2022 - Elsevier
Abstract Notoginsenoside R1 (NGR1) is the main monomeric component extracted from the
dried roots and rhizomes of Panax notoginseng, and exerts pharmacological action against …

[HTML][HTML] Protective effects and target network analysis of ginsenoside Rg1 in cerebral ischemia and reperfusion injury: a comprehensive overview of experimental …

W Xie, P Zhou, Y Sun, X Meng, Z Dai, G Sun, X Sun - Cells, 2018 - mdpi.com
Cerebral ischemia-reperfusion is a complicated pathological process. The injury and
cascade reactions caused by cerebral ischemia and reperfusion are characterized by high …

Multifaceted role of polyphenols in the treatment and management of neurodegenerative diseases

F Islam, MM Islam, AFK Meem, MH Nafady, MR Islam… - Chemosphere, 2022 - Elsevier
Neurodegenerative diseases (NDDs) are conditions that cause neuron structure and/or
function to deteriorate over time. Genetic alterations may be responsible for several NDDs …

Effects and mechanisms of compound Chinese medicine and major ingredients on microcirculatory dysfunction and organ injury induced by ischemia/reperfusion

JY Han, Q Li, ZZ Ma, JY Fan - Pharmacology & therapeutics, 2017 - Elsevier
Microcirculation dysfunction and organ injury after ischemia and reperfusion (I/R) result from
a complex pathologic process consisting of multiple links, with metabolism impairment in the …

Nano-traditional Chinese medicine: a promising strategy and its recent advances

D Wei, H Yang, Y Zhang, X Zhang, J Wang… - Journal of Materials …, 2022 - pubs.rsc.org
Traditional Chinese Medicine (TCM) has been applied to the prevention and treatment of
numerous diseases and has an irreplaceable role in rehabilitation and health care …

[HTML][HTML] Dodging blood brain barrier with “nano” warriors: Novel strategy against ischemic stroke

S Parvez, M Kaushik, M Ali, MM Alam, J Ali… - Theranostics, 2022 - ncbi.nlm.nih.gov
Ischemic stroke (IS) is one of the leading causes of death and disability resulting in
inevitable burden globally. Ischemic injury initiates cascade of pathological events …