Cystic fibrosis (CF) is a recessive genetic disease caused by mutations in a gene encoding
a protein called Cystic Fibrosis Transmembrane Conductance Regulator (CFTR). The CFTR …

Cystic fibrosis is an autosomal recessive disease caused by mutations of the gene encoding
the cystic fibrosis transmembrane conductance regulator (CFTR). Here we summarize, at the …

The penetration behavior of nanoparticles in mucous depends on physicochemical
properties of the nanoparticles and the mucus microenvironment, due to particle–mucin …

Kidneys are central in the regulation of multiple physiological functions, such as removal of
metabolic wastes and toxins, maintenance of electrolyte and fluid balance, and control of pH …

The introduction of mutation-specific combination therapy with the cystic fibrosis
transmembrane conductance regulator (CFTR) modulators elexacaftor/tezacaftor/ivacaftor …

Cystic fibrosis is a hereditary disease that mainly affects secretory organs in humans. It is
caused by mutations in the gene encoding CFTR with the most common phenylalanine …

The major pathogen Staphylococcus aureus has to cope with host‐derived oxidative stress
to cause infections in humans. Here, we report that S. aureus tolerates high concentrations …

In cystic fibrosis (CF), defects in the CF transmembrane conductance regulator (CFTR)
channel lead to an acidic airway surface liquid (ASL), which compromises innate defence …

Since most current studies have focused on exploring how phagocyte internalization of drug-
loaded nanovesicles by macrophages would affect the function and therapeutic effects of …

The airway surface liquid (ASL) is a thin sheet of fluid that covers the luminal aspect of the
airway epithelium. The ASL is a site of several first-line host defenses, and its composition is …