Abstract CD4+ T helper (Th) cells are critical for proper immune cell homeostasis and host
defense, but are also major contributors to pathology of autoimmune and inflammatory …

Long noncoding RNA (lncRNA), with size larger than 200 nucleotides, is a new class of
noncoding RNA. Emerging evidence has revealed that lncRNAs play a key role in the …

Cytokines play a pivotal role in the pathogenesis of autoimmune diseases. The precise
triggers for the breakdown of self-tolerance and the subsequent events leading to the …

Multiple sclerosis (MS) is a chronic inflammatory demyelinating disease of the central
nervous system with a pathogenesis involving a dysfunctional blood-brain barrier and …

Objective: To elucidate the potential causality of leukocyte telomere length (LTL) with
immune-mediated inflammatory diseases (IMIDs), we conducted a Mendelian randomization …

Telomeres are specialized nucleoprotein structures located at the end of linear
chromosomes and telomerase is the enzyme responsible for telomere elongation …

In the preantibiotic era, TB of the skin was treated successfully with UV light. By the 1920s,
pulmonary TB was being treated with regular sun exposure. During the last decade, basic …

Chronic inflammatory responses in the lungs contribute to the development and progression
of chronic obstructive pulmonary disease (COPD). Although research studies focused …

Citation Kwak‐Kim J, Park JC, Ahn HK, Kim JW, Gilman‐Sachs A. Immunological modes of
pregnancy loss. Am J Reprod Immunol 2010 During the implantation period, a significant …

Nervonic acid, a 24-carbon fatty acid with only one double bond at the 9th carbon (C24: 1n-
9), is abundant in the human brain, liver, and kidney. It not only functions in free form but …