Allogeneic haematopoietic cell transplantation for myelofibrosis: proposed definitions and management strategies for graft failure, poor graft function and relapse: best …

DP McLornan, JC Hernandez-Boluda, T Czerw… - Leukemia, 2021 - nature.com
Allogeneic haematopoietic cell transplantation (allo-HCT) remains the only curative
approach in myelofibrosis (MF). Despite advances over recent decades, relapse and non …

Chimerism analysis for clinicians: a review of the literature and worldwide practices

AG Blouin, M Askar - Bone marrow transplantation, 2022 - nature.com
This review highlights literature pertinent to chimerism analysis in the context of
hematopoietic cell transplantation (HCT). We also conducted a survey of testing practices of …

2021 Update on allogeneic hematopoietic stem cell transplant for myelofibrosis: a review of current data and applications on risk stratification and management

H Ali, A Bacigalupo - American Journal of Hematology, 2021 - Wiley Online Library
The number of patients with myelofibrosis (MF) undergoing an allogeneic hemopoietic stem
cell transplantation (HSCT) is increasing: in the analysis of the European Group for Blood …

[HTML][HTML] Monitoring measurable residual disease and chimerism in patients with JAK2 V617F-positive myelofibrosis after allogeneic hematopoietic cell transplantation

JM Lee, A Ahn, EJ Min, SE Lee, M Kim, Y Kim - Blood Cancer Journal, 2023 - nature.com
Dear Editor, Myelofibrosis (MF) is the most severe form of myeloproliferative neoplasm
(MPN). Allogeneic hematopoietic stem cell transplantation (allo-HCT) is the only known …

Innovative strategies to improve hematopoietic stem cell transplant outcomes in myelofibrosis

J Perram, DM Ross, D McLornan… - American Journal of …, 2022 - Wiley Online Library
Myelofibrosis (MF) is a clonal myeloproliferative neoplasm characterized by inflammation,
marrow fibrosis, and an inherent risk of blastic transformation. Hematopoietic allogeneic …

Full donor chimerism after allogeneic hematopoietic stem cells transplant for myelofibrosis: the role of the conditioning regimen

P Chiusolo, S Bregante, S Giammarco… - American Journal of …, 2021 - Wiley Online Library
The aim of this retrospective study was to assess the rate of full donor chimerism (F‐DC) in
patients with myelofibrosis, prepared for an allogeneic stem cell transplant, with one or two …

[HTML][HTML] Early post-transplantation factors predict survival outcomes in patients undergoing allogeneic hematopoietic cell transplantation for myelofibrosis

T Jain, KL Kunze, L Mountjoy, DK Partain… - Blood cancer …, 2020 - nature.com
Factors predicting allogeneic hematopoietic cell transplantation (HCT) outcomes in
myelofibrosis in the early post-HCT period have not been defined thus far. We attempt to …

[HTML][HTML] Early mixed lymphoid donor/host chimerism is associated with improved transplant outcome in patients with primary or secondary myelofibrosis

HJ Deeg, RB Salit, T Monahan, G Schoch… - Biology of Blood and …, 2020 - Elsevier
We investigated risk factors for the development of mixed chimerism in 131 patients who
underwent transplantation for myelofibrosis and determined the impact of lymphoid (CD3+) …

Are transplant indications changing for myelofibrosis?

J Palmer - Hematology, 2023 - ashpublications.org
Myelofibrosis is a devastating myeloid malignancy characterized by dysregulation of the JAK-
STAT pathway, resulting in splenomegaly, constitutional symptoms, anemia …

[HTML][HTML] Does mixed chimerism after allogeneic hematopoietic cell transplantation in pediatric patients with Fanconi anemia impact on outcome?

M Ayas, K Siddiqui, A Al-Jefri, A Al-Ahmari… - … and Cellular Therapy, 2021 - Elsevier
Fanconi anemia (FA) cells are characterized by genomic instability, which places FA
patients at risk for malignancies such as leukemia and oropharyngeal/urogenital cancers …