Tailoring materials for modulation of macrophage fate
Human immune system acts as a pivotal role in the tissue homeostasis and disease
progression. Immunomodulatory biomaterials that can manipulate innate immunity and …
progression. Immunomodulatory biomaterials that can manipulate innate immunity and …
Overcoming the blood–brain barrier: the role of nanomaterials in treating neurological diseases
Therapies directed toward the central nervous system remain difficult to translate into
improved clinical outcomes. This is largely due to the blood–brain barrier (BBB), arguably …
improved clinical outcomes. This is largely due to the blood–brain barrier (BBB), arguably …
Material design for lymph node drug delivery
A significant fraction of the total immune cells in the body are located in several hundred
lymph nodes, in which lymphocyte accumulation, activation and proliferation are organized …
lymph nodes, in which lymphocyte accumulation, activation and proliferation are organized …
Spatial density and distribution of tumor-associated macrophages predict survival in non–small cell lung carcinoma
The respective antitumoral and protumoral roles of M1 and M2 tumor-associated
macrophages (TAM) typify the complexity of macrophage function in cancer. In lung cancer …
macrophages (TAM) typify the complexity of macrophage function in cancer. In lung cancer …
Pharmaceutical liposomal drug delivery: a review of new delivery systems and a look at the regulatory landscape
C Zylberberg, S Matosevic - Drug delivery, 2016 - Taylor & Francis
Liposomes were the first nanoscale drug to be approved for clinical use in 1995. Since then,
the technology has grown considerably, and pioneering recent work in liposome-based …
the technology has grown considerably, and pioneering recent work in liposome-based …
Biodegradable polymers in drug delivery and oral vaccination
Over the years biodegradable polymers have emerged as promising polymeric materials in
drug delivery and vaccination due to their fascinating properties like biocompatibility …
drug delivery and vaccination due to their fascinating properties like biocompatibility …
Dynamic Biodistribution of Extracellular Vesicles in Vivo Using a Multimodal Imaging Reporter
CP Lai, O Mardini, M Ericsson, S Prabhakar… - ACS …, 2014 - ACS Publications
Extracellular vesicles (EVs) are nanosized vesicles released by normal and diseased cells
as a novel form of intercellular communication and can serve as an effective therapeutic …
as a novel form of intercellular communication and can serve as an effective therapeutic …
Curcumin nanoformulations: a review of pharmaceutical properties and preclinical studies and clinical data related to cancer treatment
Curcumin, a natural yellow phenolic compound, is present in many kinds of herbs,
particularly in Curcuma longa Linn.(turmeric). It is a natural antioxidant and has shown many …
particularly in Curcuma longa Linn.(turmeric). It is a natural antioxidant and has shown many …
Harnessing inhaled nanoparticles to overcome the pulmonary barrier for respiratory disease therapy
The lack of effective treatments for pulmonary diseases presents a significant global health
burden, primarily due to the challenges posed by the pulmonary barrier that hinders drug …
burden, primarily due to the challenges posed by the pulmonary barrier that hinders drug …
Interaction between virus-like particles (VLPs) and pattern recognition receptors (PRRs) from dendritic cells (DCs): toward better engineering of VLPs
J Zepeda-Cervantes, JO Ramírez-Jarquín… - Frontiers in …, 2020 - frontiersin.org
Virus-like particles (VLPs) have been shown to be strong activators of dendritic cells (DCs).
DCs are the most potent antigen presenting cells (APCs) and their activation prompts the …
DCs are the most potent antigen presenting cells (APCs) and their activation prompts the …