The microbiome, cancer, and cancer therapy

BA Helmink, MAW Khan, A Hermann… - Nature medicine, 2019 - nature.com
With the advent of next-generation sequencing, we have an unprecedented ability to study
tumor and host genomes as well as those of the vast array of microorganisms that exist …

Culturing the human microbiota and culturomics

JC Lagier, G Dubourg, M Million, F Cadoret… - Nature Reviews …, 2018 - nature.com
The gut microbiota has an important role in the maintenance of human health and in disease
pathogenesis. This importance was realized through the advent of omics technologies and …

Role of zinc in immune system and anti-cancer defense mechanisms

D Skrajnowska, B Bobrowska-Korczak - Nutrients, 2019 - mdpi.com
The human body cannot store zinc reserves, so a deficiency can arise relatively quickly, eg,
through an improper diet. Severe zinc deficiency is rare, but mild deficiencies are common …

Oral nanomedicine for modulating immunity, intestinal barrier functions, and gut microbiome

Y Lee, N Kamada, JJ Moon - Advanced drug delivery reviews, 2021 - Elsevier
The gastrointestinal tract (GIT) affects not only local diseases in the GIT but also various
systemic diseases. Factors that can affect the health and disease of both GIT and the human …

[HTML][HTML] Gut microbiome in gastrointestinal cancer: a friend or foe?

Y Liu, Y Baba, T Ishimoto, X Gu, J Zhang… - … Journal of Biological …, 2022 - ncbi.nlm.nih.gov
The impact of the gut microbiome on host health is becoming increasingly recognized. To
date, there is growing evidence that the complex characteristics of the microbial community …

Dysbiosis of gut microbiota in promoting the development of colorectal cancer

S Zou, L Fang, MH Lee - Gastroenterology report, 2018 - academic.oup.com
Gastrointestinal microbiome, containing at least 100 trillion bacteria, resides in the mucosal
surface of human intestine. Recent studies show that perturbations in the microbiota may …

The impacts of natural polysaccharides on intestinal microbiota and immune responses–a review

C Tang, R Ding, J Sun, J Liu, J Kan, C Jin - Food & function, 2019 - pubs.rsc.org
In recent years, natural polysaccharides have received increasing attention and become
one type of popular dietary nutrient because of their various biological functions. In this …

Microbiome or infections: amyloid-containing biofilms as a trigger for complex human diseases

AL Miller, S Bessho, K Grando, Ç Tükel - Frontiers in Immunology, 2021 - frontiersin.org
The human microbiota is the community of microorganisms that live upon or within their
human host. The microbiota consists of various microorganisms including bacteria, fungi …

Gut microbiota-derived indole 3-propionic acid protects against radiation toxicity via retaining acyl-CoA-binding protein

H Xiao, M Cui, Y Li, J Dong, S Zhang, C Zhu, M Jiang… - Microbiome, 2020 - Springer
Background We have proved fecal microbiota transplantation (FMT) is an efficacious remedy
to mitigate acute radiation syndrome (ARS); however, the mechanisms remain incompletely …

Protein lysine crotonylation: past, present, perspective

G Jiang, C Li, M Lu, K Lu, H Li - Cell death & disease, 2021 - nature.com
Lysine crotonylation has been discovered in histone and non-histone proteins and found to
be involved in diverse diseases and biological processes, such as neuropsychiatric disease …