Transcript termination is essential for accurate gene expression and the removal of RNA
polymerase (RNAP) at the ends of transcription units. In bacteria, two mechanisms are …

Efficient and accurate termination is required for gene transcription in all living organisms,.
Cellular RNA polymerases in both bacteria and eukaryotes can terminate their transcription …

The rates of RNA synthesis and the folding of nascent RNA into biologically active structures
are linked via pausing by RNA polymerase (RNAP). Structures that form within the RNA-exit …

Growing RNAs fold differently as they are transcribed, which modulates their finally adopted
structures. Riboswitches regulate gene expression by structural change, which are sensitive …

An experimental system was designed to measure in vivo termination efficiency (TE) of the
Rho-independent terminator and position–function relations were quantified for the …

Bacteriophages typically hijack the host bacterial transcriptional machinery to regulate their
own gene expression and that of the host bacteria. The structural basis for bacteriophage …

Intrinsic transcription termination (ITT) sites are currently identified by locating single and
double-adjacent RNA hairpins downstream of the stop codon. ITTs for a limited number of …

Abstract RNA polymerase (RNAP) III synthesizes tRNAs and other transcripts, and mutations
to its subunits cause human disorders. The RNAP III subunit-heterodimer C37/53 functions …

Riboswitches are RNA residue segments located in untranslated regions of messenger
RNAs. These folded segments directly bind ligands through shape complementarity and …

In bacteria, intrinsic termination signals cause disassembly of the highly stable elongating
transcription complex (EC) over windows of two to three nucleotides after kilobases of RNA …