mTOR signaling-related microRNAs as cardiac hypertrophy modulators in high-volume endurance training

BRA Pelozin, UPR Soci, JLP Gomes… - Journal of Applied …, 2022 - journals.physiology.org
Aerobic exercise training (ET) promotes cardiovascular adaptations, including physiological
left ventricular hypertrophy (LVH). However, the molecular mechanisms underlying these …

Next‐generation sequencing reveals that miR‐16‐5p, miR‐19a‐3p, miR‐451a, and miR‐25‐3p cargo in plasma extracellular vesicles differentiates sedentary young …

M Fernandez‐Sanjurjo… - European Journal of …, 2024 - Wiley Online Library
A sedentary lifestyle and Olympic participation are contrary risk factors for global mortality
and incidence of cancer and cardiovascular disease. Extracellular vesicle miRNAs have …

Distinct plasma gradients of microRNA-204 in the pulmonary circulation of patients suffering from WHO Groups I and II pulmonary hypertension

LE Estephan, MV Genuardi… - Pulmonary …, 2019 - journals.sagepub.com
Pulmonary hypertension (PH), a heterogeneous vascular disease, consists of subtypes with
overlapping clinical phenotypes. MicroRNAs, small non-coding RNAs that negatively …

Circulating microRNA levels after exercise-induced muscle damage and the repeated bout effect

E Chalchat, V Martin, K Charlot… - American Journal …, 2023 - journals.physiology.org
The neuromuscular system can quickly adapt to exercise-induced muscle damage (EIMD),
such that it is less affected by subsequent damaging exercise, a phenomenon known as the …

Circulating microRNAs: advances in exercise physiology

RM Sapp, JM Hagberg - Current Opinion in Physiology, 2019 - Elsevier
Circulating microRNAs (ci-miRs) are post-transcriptional regulators of gene expression
released by cells into blood or other biofluids. Acute and chronic exercise have been shown …

A single session of EMS training induces long-lasting changes in circulating muscle but not cardiovascular miRNA levels: a randomized crossover study

S Biss, M Teschler, M Heimer, T Thum… - Journal of Applied …, 2023 - journals.physiology.org
Electromyostimulation (EMS) is used to maintain or build skeletal muscle and to increase
cardiopulmonary fitness. Only limited data on the molecular mechanisms induced by EMS …

Impacts of circulating microRNAs in exercise-induced vascular remodeling

GP Van Guilder, CC Preston… - American Journal of …, 2021 - journals.physiology.org
Cardiovascular adaptation underlies all athletic training modalities, with a variety of factors
contributing to overall response during exercise-induced stimulation. In this regard the role …

miRNAs as markers for the development of individualized training regimens: A pilot study

M Widmann, F Mattioni Maturana… - Physiological …, 2022 - Wiley Online Library
Small, non‐coding RNAs (microRNAs) have been shown to regulate gene expression in
response to exercise in various tissues and organs, thus possibly coordinating their adaptive …

Bone–muscle crosstalk following exercise plus Ursolic acid by myomiR-133a/Cx43-Runx2 axis in aged type 2 diabetes rat models

MA Farsani, E Banitalebi, M Faramarzi… - Chemico-Biological …, 2023 - Elsevier
Natural bioactive compound, Ursolic acid (UA), plus different types of exercise may exert the
action on glycemic control, leading to clinical benefits in the prevention and treatment of …

Biomarker-based approach to determine etiology and severity of pulmonary hypertension: Focus on microRNA

S Rogula, B Pomirski, N Czyżak, C Eyileten… - Frontiers in …, 2022 - frontiersin.org
Pulmonary arterial hypertension (PAH) is characterized by remodeling of the pulmonary
arteries, and defined by elevated pulmonary arterial pressure, measured during right heart …