Lipid-based nanoparticles for drug/gene delivery: An overview of the production techniques and difficulties encountered in their industrial development

M Mehta, TA Bui, X Yang, Y Aksoy, EM Goldys… - ACS Materials …, 2023 - ACS Publications
Over the past decade, the therapeutic potential of nanomaterials as novel drug delivery
systems complementing conventional pharmacology has been widely acknowledged …

[HTML][HTML] Rise of the RNA machines–self-amplification in mRNA vaccine design

JDG Comes, GP Pijlman, TAH Hick - Trends in Biotechnology, 2023 - cell.com
Abstract mRNA vaccines have won the race for early COVID-19 vaccine approval, yet
improvements are necessary to retain this leading role in combating infectious diseases. A …

A state-of-the-art review on solid lipid nanoparticles as a nanovaccines delivery system

M Assefi, M Ataeinaeini, A Nazari, A Gholipour… - Journal of Drug Delivery …, 2023 - Elsevier
In the design of vaccine generation, significant attempts have been made to produce novel
vaccines and, as well, to increase the effectiveness of available vaccines versus particular …

[HTML][HTML] Biosynthesis of Bixa orellana seed extract mediated silver nanoparticles with moderate antioxidant, antibacterial and antiproliferative activity

B Maitra, MH Khatun, F Ahmed, N Ahmed… - Arabian Journal of …, 2023 - Elsevier
Biosynthesis of metallic silver nanoparticles (AgNPs) has gained much interest and offers an
attractive alternate to physical and chemical approaches. In recent year several safe, easy …

[HTML][HTML] Multifunctional lipid-based nanoparticles for wound healing and antibacterial applications: A review

F Motsoene, H Abrahamse, SSD Kumar - Advances in colloid and interface …, 2023 - Elsevier
Wound healing primarily involves preventing severe infections, accelerating healing, and
reducing pain and scarring. Therefore, the multifunctional application of lipid-based …

[HTML][HTML] Biomaterials-mediated CRISPR/Cas9 delivery: recent challenges and opportunities in gene therapy

AK Dubey, E Mostafavi - Frontiers in Chemistry, 2023 - frontiersin.org
The use of biomaterials in delivering CRISPR/Cas9 for gene therapy in infectious diseases
holds tremendous potential. This innovative approach combines the advantages of …

[HTML][HTML] Nanostructured lipid carrier system: A compendium of their formulation development approaches, optimization strategies by quality by design, and recent …

S Javed, B Mangla, Y Almoshari, MH Sultan… - Nanotechnology …, 2022 - degruyter.com
The lipid-based colloidal carriers, such as nanostructured lipid carriers (NLCs), solid lipid
nanoparticles (SLNs), nanocapsules, liposomes, and microemulsion, are the latest and …

[HTML][HTML] Anticancer applications of essential oils formulated into lipid-based delivery nanosystems

J Jampilek, K Kralova - Pharmaceutics, 2022 - mdpi.com
The use of natural compounds is becoming increasingly popular among patients, and there
is a renewed interest among scientists in nature-based bioactive agents. Traditionally …

[HTML][HTML] Fluorescent multifunctional organic nanoparticles for drug delivery and bioimaging: a tutorial review

G Vargas-Nadal, M Köber, A Nsamela, F Terenziani… - Pharmaceutics, 2022 - mdpi.com
Fluorescent organic nanoparticles (FONs) are a large family of nanostructures constituted by
organic components that emit light in different spectral regions upon excitation, due to the …

[HTML][HTML] Novel hydrogels for topical applications: An updated comprehensive review based on source

Y Almoshari - Gels, 2022 - mdpi.com
Active pharmaceutical ingredients (API) or drugs are normally not delivered as pure
chemical substances (for the prevention or the treatment of any diseases). APIs are still …