Although recurrent miscarriage (RM) affects only 1–3% of couples, it has a major influence
on the wellbeing and psychosocial status of patients. Therefore, research into improved …

About 17% of couples suffer from infertility conditions, worldwide. The most common
reasons for female infertility are ovulation disorders, fallopian-related disorders, RM, RIF …

Due to the expression of paternal antigens by the embryo, pregnancy is considered as a
semi‐allograft and so immunological dysregulation is considered as one of the important …

Problem The efficacy of lymphocyte immunotherapy (LIT) for unexplained recurrent
miscarriage (uRM) remains indefinite. The objective of the present study is to …

Uterine fibroids are benign tumours, which are associated with subfertility and early
pregnancy loss. This study was carried out to examine the effect of submucous fibroids on …

Progesterone is crucial for the establishment and maintenance of pregnancy. Progesterone-
regulated genes in the pregnant uterus control the development of endometrial receptivity as …

Problem Lymphocyte immunotherapy (LIT) emerged in the early 1980s as a new therapeutic
proposal for couples with a history of recurrent miscarriages (RM). However, in the early …

Recurrent spontaneous miscarriage (RSM) and idiopathic infertility (IIF) are partially caused
by immunologic disturbances. Paternal lymphocyte immunization (PLI) is proposed for …

Problem We set out to determine whether intravenous immunoglobulin (IVIG) improves in
vitro fertilization (IVF) success rates in women with a difficult history of multiple (≥ 2) prior …

Since the days of Medawar, the goal of therapeutic tolerogenesis has been a “Holy Grail” for
immunologists. While knowledge of cellular and molecular mechanisms of this process has …