Immunomodulation by human milk oligosaccharides: the potential role in prevention of allergic diseases

M Zuurveld, NP Van Witzenburg, J Garssen… - Frontiers in …, 2020 - frontiersin.org
The prevalence and incidence of allergic diseases is rising and these diseases have
become the most common chronic diseases during childhood in Westernized countries …

The rise of food allergy: Environmental factors and emerging treatments

S Benedé, AB Blázquez, D Chiang, L Tordesillas… - …, 2016 - thelancet.com
Food allergy has rapidly increased in prevalence, suggesting an important role for
environmental factors in disease susceptibility. The immune response of food allergy is …

[HTML][HTML] Mechanisms underlying immune effects of dietary oligosaccharides

PV Jeurink, BCAM van Esch, A Rijnierse… - The American journal of …, 2013 - Elsevier
The WHO refers to human milk as the nutritional gold standard for term infants. Human milk
contains many immunomodulatory compounds, including oligosaccharides. Human-milk …

In Vitro Evidence for Immune-Modulatory Properties of Non-Digestible Oligosaccharides: Direct Effect on Human Monocyte Derived Dendritic Cells

S Lehmann, J Hiller, J van Bergenhenegouwen… - PLoS …, 2015 - journals.plos.org
Infant formulas containing non-digestible oligosaccharides (NDO) similar to the composition
in breast milk or a combination of lactic acid bacteria (LAB) and NDO have been shown to …

Human milk oligosaccharides attenuate antigen–antibody complex induced chemokine release from human intestinal epithelial cell lines

S Zehra, I Khambati, M Vierhout, MF Mian… - Journal of Food …, 2018 - Wiley Online Library
There has been increased interest in the use of dietary ingredients, including prebiotics such
as human‐milk oligosaccharides (HMOs), as therapeutic strategies for food allergy …

Milk: a postnatal imprinting system stabilizing FoxP3 expression and regulatory T cell differentiation

BC Melnik, SM John, P Carrera-Bastos… - Clinical and translational …, 2016 - Springer
Background Breastfeeding has protective effects for the development of allergies and atopy.
Recent evidence underlines that consumption of unboiled farm milk in early life is a key …

Mesenteric IL-10-producing CD5+ regulatory B cells suppress cow's milk casein-induced allergic responses in mice

AR Kim, HS Kim, DK Kim, ST Nam, HW Kim, YH Park… - Scientific reports, 2016 - nature.com
Food allergy is a hypersensitive immune reaction to food proteins. We have previously
demonstrated the presence of IL-10-producing CD5+ B cells and suggested their potential …

Role of cellular immunity in cow's milk allergy: pathogenesis, tolerance induction, and beyond

J Jo, J Garssen, L Knippels… - Mediators of …, 2014 - Wiley Online Library
Food allergy is an aberrant immune‐mediated reaction against harmless food substances,
such as cow's milk proteins. Due to its very early introduction, cow's milk allergy is one of the …

[HTML][HTML] Supplementing pregnant mice with a specific mixture of nondigestible oligosaccharides reduces symptoms of allergic asthma in male offspring

A Hogenkamp, S Thijssen, N van Vlies, J Garssen - The Journal of Nutrition, 2015 - Elsevier
Background: Previously, maternal supplementation with short-chain galacto-and long-chain
fructo-oligosaccharides (scGOS/lcFOS; ratio 9: 1) was shown to affect maternal and fetal …

CD 25+ regulatory T cells transfer n‐3 long chain polyunsaturated fatty acids‐induced tolerance in mice allergic to cow's milk protein

LWJ Van den Elsen, L Meulenbroek, B van Esch… - Allergy, 2013 - Wiley Online Library
Background Recently, we have shown that dietary long‐chain n‐3 polyunsaturated fatty
acids (n‐3 LCPUFA) largely prevent allergic sensitization in a murine model for cow's milk …