[HTML][HTML] The G Protein-Coupled Estrogen Receptor (GPER): a critical therapeutic target for cancer
KA Hall, EJ Filardo - Cells, 2023 - mdpi.com
Estrogens have been implicated in the pathogenesis of various cancers, with increasing
concern regarding the overall rising incidence of disease and exposure to environmental …
concern regarding the overall rising incidence of disease and exposure to environmental …
[HTML][HTML] Microbiota composition and its impact on DNA methylation in colorectal cancer
M Gutierrez-Angulo, ML Ayala-Madrigal… - Frontiers in …, 2023 - frontiersin.org
Colorectal cancer is a complex disease resulting from the interaction of genetics,
epigenetics, and environmental factors. DNA methylation is frequently found in tumor …
epigenetics, and environmental factors. DNA methylation is frequently found in tumor …
DNA damage resulting from human endocrine disrupting chemical exposure: Genotoxicity, detection and dietary phytochemical intervention
X Li, N Zang, N Zhang, L Pang, L Lv, X Meng, X Lv… - Chemosphere, 2023 - Elsevier
In recent years, exposure to endocrine disrupting chemicals (EDCs) has posed an
increasing threat to human health. EDCs are major risk factors in the occurrence and …
increasing threat to human health. EDCs are major risk factors in the occurrence and …
[HTML][HTML] Genetic risk impacts the association of menopausal hormone therapy with colorectal cancer risk
Y Tian, Y Lin, C Qu, V Arndt, JW Baurley… - British journal of …, 2024 - nature.com
Background Menopausal hormone therapy (MHT), a common treatment to relieve symptoms
of menopause, is associated with a lower risk of colorectal cancer (CRC). To inform CRC …
of menopause, is associated with a lower risk of colorectal cancer (CRC). To inform CRC …
[HTML][HTML] Effect of miR-34a on the expression of clock and clock-controlled genes in DLD1 and Lovo human cancer cells with different backgrounds with respect to p53 …
R Moravčík, S Olejárová, J Zlacká, I Herichová - Plos one, 2023 - journals.plos.org
The small non-coding RNA miR-34a is a p53-regulated miRNA that acts as a tumour
suppressor of colorectal cancer (CRC). Oncogenesis is also negatively influenced by …
suppressor of colorectal cancer (CRC). Oncogenesis is also negatively influenced by …
[HTML][HTML] Sex differences in colorectal cancer: with a focus on sex hormone–gut microbiome axis
Z Wu, Y Huang, R Zhang, C Zheng, F You… - Cell Communication and …, 2024 - Springer
Sexual dimorphism has been observed in the incidence and prognosis of colorectal cancer
(CRC), with men generally exhibiting a slightly higher incidence than women. Research …
(CRC), with men generally exhibiting a slightly higher incidence than women. Research …
[HTML][HTML] Genistein–Aspirin Combination Exerts Cytotoxic and Anti-Migratory Effects in Human Colorectal Cancer Cells
C Iftode, S Iurciuc, I Marcovici, I Macasoi, D Coricovac… - Life, 2024 - mdpi.com
Colorectal cancer (CRC) is a heterogenous pathology with high incidence and mortality
rates globally, but it is also preventable so finding the most promising candidates (natural …
rates globally, but it is also preventable so finding the most promising candidates (natural …
[HTML][HTML] Insights on the association between thyroid diseases and colorectal cancer
F Gagliardi, E Baldini, E Lori, S Cardarelli… - Journal of Clinical …, 2023 - mdpi.com
Benign and malignant thyroid diseases (TDs) have been associated with the occurrence of
extrathyroidal malignancies (EMs), including colorectal cancers (CRCs). Such associations …
extrathyroidal malignancies (EMs), including colorectal cancers (CRCs). Such associations …
[HTML][HTML] Sexual dimorphism in colorectal cancer: molecular mechanisms and treatment strategies
Y Rodríguez-Santiago, CA Garay-Canales… - Biology of Sex …, 2024 - Springer
Introduction Sexual dimorphism significantly influences cancer incidence and prognosis.
Notably, females exhibit a lower risk and favorable prognosis for non-reproductive cancers …
Notably, females exhibit a lower risk and favorable prognosis for non-reproductive cancers …
Regulation of bone homeostasis by traditional Chinese medicine active scaffolds and enhancement for the osteoporosis bone regeneration
Ethnopharmacological relevance The active ingredients of traditional Chinese medicine
(TCM), such as naringin (NG), Eucommiol, isopsoralen, icariin, Astragalus polysaccharides …
(TCM), such as naringin (NG), Eucommiol, isopsoralen, icariin, Astragalus polysaccharides …