Management of nasopharyngeal carcinoma: current practice and future perspective

AWM Lee, BBY Ma, WT Ng, ATC Chan - Journal of clinical oncology, 2015 - ascopubs.org
Nasopharyngeal carcinoma of the undifferentiated subtype is endemic to southern China,
and patient prognosis has improved significantly over the past three decades because of …

Chemotherapy and chemo-resistance in nasopharyngeal carcinoma

S Guan, J Wei, L Huang, L Wu - European Journal of Medicinal Chemistry, 2020 - Elsevier
Nasopharyngeal carcinoma (NPC) is closely associated with Epstein-Barr virus (EBV) and
occurs frequently in the south of China and Southeast Asian countries. Concurrent chemo …

Current management of nasopharyngeal cancer

AWM Lee, JC Lin, WT Ng - Seminars in radiation oncology, 2012 - Elsevier
Management of nasopharyngeal carcinoma is one of the greatest clinical challenges.
Appropriate detection is not easy because of its anatomical location; sensitive biomarkers in …

[HTML][HTML] Plasma Epstein–Barr viral DNA load at midpoint of radiotherapy course predicts outcome in advanced-stage nasopharyngeal carcinoma

SF Leung, KCA Chan, BB Ma, EP Hui, F Mo… - Annals of oncology, 2014 - Elsevier
Background To test the hypothesis that prognostication of treatment outcome is feasible by
biomarker response at midcourse of chemoradiotherapy (CRT)/radiotherapy (RT), with …

The battle against nasopharyngeal cancer

AWM Lee, WT Ng, YH Chan, H Sze, C Chan… - Radiotherapy and …, 2012 - Elsevier
This is a review of the evolving efforts to understand and combat nasopharyngeal carcinoma
(NPC), a most peculiar cancer with a distinctly skewed geographic and ethnic distribution …

[HTML][HTML] FGF-2 signaling in nasopharyngeal carcinoma modulates pericyte-macrophage crosstalk and metastasis

Y Wang, Q Sun, Y Ye, X Sun, S Xie, Y Zhan, J Song… - JCI insight, 2022 - ncbi.nlm.nih.gov
Molecular signaling in the tumor microenvironment (TME) is complex, and crosstalk among
various cell compartments in supporting metastasis remains poorly understood. In particular …

Long‐term outcomes after reirradiation in nasopharyngeal carcinoma with intensity‐modulated radiotherapy: a meta‐analysis

YH Leong, YY Soon, KM Lee, LC Wong… - Head & …, 2018 - Wiley Online Library
Background The purpose of this clinical review was to summate the published data for the
long‐term outcomes of reirradiation with intensity‐modulated radiotherapy (IMRT) for locally …

Emerging treatment options for nasopharyngeal carcinoma

L Zhang, QY Chen, H Liu, LQ Tang… - … design, development and …, 2013 - Taylor & Francis
Nasopharyngeal carcinoma is endemic in Asia and is etiologically associated with Epstein–
Barr virus. Radiotherapy is the primary treatment modality. The role of systemic therapy has …

[HTML][HTML] Nasopharyngeal carcinoma: clinical achievements and considerations among treatment options

Z Liu, Y Chen, Y Su, X Hu, X Peng - Frontiers in oncology, 2021 - frontiersin.org
Nasopharyngeal carcinoma (NPC) is a severe malignancy arising from the nasopharyngeal
epithelium and is southern China's third most common cancer. With the advancement of …

[HTML][HTML] Anti-EGFR therapies in nasopharyngeal carcinoma

X Chen, R Liang, X Zhu - Biomedicine & Pharmacotherapy, 2020 - Elsevier
Nasopharyngeal carcinoma (NPC) is a common malignant tumor in Southern China and
South-East Asia. Regardless of initiative high response to radiotherapy, parts of patients still …