Erythroblastic islands, the specialized niches in which erythroid precursors proliferate,
differentiate, and enucleate, were first described 50 years ago by analysis of transmission …

Biochemical and molecular genetic studies have revealed that blood group antigens are
present on cell surface molecules of wide structural diversity, including carbohydrate …

Definitive erythropoiesis usually occurs in the bone marrow or fetal liver, where erythroblasts
are associated with a central macrophage in anatomical units called 'blood islands',. Late in …

The possible involvement of Fas and Fas ligand (FasL) in the regulation of erythropoiesis
was evaluated. Immunohistochemistry of normal bone marrow specimens revealed that …

OBJECTIVE: Erythropoiesis is positively regulated by stem cell factor, interleukin 3, and
erythropoietin, which synergize to allow the production of hemoglobinized red blood cells …

We investigated roles of α4 integrins during hematopoiesis using mutant and chimeric mice.
Yolk sac erythropoiesis and migration of hematopoietic progenitors to fetal liver, spleen, and …

In mammals, the functional unit for definitive erythropoiesis is the erythroblastic island, a
multicellular structure composed of a central macrophage surrounded by developing …

Erythropoiesis occurs in erythroblastic islands, where developing erythroblasts closely
interact with macrophages. The adhesion molecules that govern macrophage-erythroblast …

We have previously identified a novel protein that mediates the attachment of erythroblasts
to macrophages in vitro. This attachment promotes terminal maturation and enucleation of …

The non-selective mechanosensitive ion channel PIEZO1 controls erythrocyte volume
homeostasis. Different missense gain-of-function mutations in PIEZO1 gene have been …