The vast majority of the brain's vascular length is composed of capillaries, where our
understanding of blood flow control remains incomplete. This review synthesizes current …

To match the metabolic demands of the brain, mechanisms have evolved to couple neuronal
activity to vasodilation, thus increasing local cerebral blood flow and delivery of oxygen and …

The majority of the brain's vasculature is composed of intricate capillary networks lined by
capillary pericytes. However, it remains unclear whether capillary pericytes influence blood …

Deterioration of brain capillary flow and architecture is a hallmark of aging and dementia. It
remains unclear how loss of brain pericytes in these conditions contributes to capillary …

The microvasculature underlies the supply networks that support neuronal activity within
heterogeneous brain regions. What are common versus heterogeneous aspects of the …

Characterizing blood flow dynamics in vivo is critical to understanding the function of the
vascular network under physiological and pathological conditions. Existing methods for …

Blood microcirculation supplies neurons with oxygen and nutrients, and contributes to
clearing their neurotoxic waste, through a dense capillary network connected to larger tree …

Consciousness is lost within seconds upon cessation of cerebral blood flow. The brain
cannot store oxygen, and interruption of oxidative phosphorylation is fatal within minutes …

Application of NIR (near-infrared) emitting transition metal complexes in biomedicine is a
rapidly developing area of research. Emission of this class of compounds in the “optical …

Alzheimer's disease (AD) is a neurodegenerative disorder associated with continual decline
in cognition and ability to perform routine functions such as remembering familiar places or …