Nitric oxide (NO) is an important signalling molecule which modulates several biological and
pathological processes. Dimethylarginine dimethylaminohydrolase 1 (DDAH1) plays a key …

A series of 32 thiourea-based urease inhibitors were synthesized and evaluated against
native bacterial enzyme and whole cells of Sporosarcina pasteurii and Proteus mirabilis …

Catechols have been reported to be potent covalent inhibitors of ureases, and they exhibit
activity by modifying cysteine residues at the entrance to enzymatic active sites. Following …

Bacterial multiresistance to drugs is a rapidly growing global phenomenon. New resistance
mechanisms have been described in different bacterial pathogens, threatening the effective …

The research on new compounds against plant pathogens is still socially and economically
important. It results from the increasing resistance of pests to plant protection products and …

This paper reports on the molecular details of the reactivity of urease, a nickel-dependent
enzyme that catalyses the last step of organic nitrogen mineralization, with thiuram …

Antybiotyki to grupa substancji o udokumentowanej aktywności przeciwdrobnoustrojowej
produkowanych naturalnie przez inne gatunki mikroorganizmów (najczęściej grzyby …