Gender differences in sepsis: cardiovascular and immunological aspects

MK Angele, S Pratschke, WJ Hubbard, IH Chaudry - Virulence, 2014 - Taylor & Francis
During sepsis, a complex network of cytokine, immune, and endothelial cell interactions
occur and disturbances in the microcirculation cause organ dysfunction or even failure …

[HTML][HTML] Liver disease in women: the influence of gender on epidemiology, natural history, and patient outcomes

J Guy, MG Peters - Gastroenterology & hepatology, 2013 - ncbi.nlm.nih.gov
Women more commonly present with acute liver failure, autoimmune hepatitis, benign liver
lesions, primary biliary cirrhosis, and toxin-mediated hepatotoxicity. Women less commonly …

The role of sex in acute and chronic liver damage

K Sayaf, D Gabbia, FP Russo, S De Martin - International Journal of …, 2022 - mdpi.com
Acute and chronic hepatic damages are caused by xenobiotics or different diseases
affecting the liver, characterized by different etiologies and pathological features. It has been …

The role of epigenetics in primary biliary cholangitis

A Gerussi, EM Paraboschi, C Cappadona… - International Journal of …, 2022 - mdpi.com
Primary Biliary Cholangitis (PBC) is a rare autoimmune disease of the liver, affecting mostly
females. There is evidence that epigenetic changes have a pathogenic role in PBC …

Gender differences in liver disease and the drug-dose gender gap

E Buzzetti, PM Parikh, A Gerussi… - Pharmacological Research, 2017 - Elsevier
Although gender-based medicine is a relatively recent concept, it is now emerging as an
important field of research, supported by the finding that many diseases manifest differently …

The role of natural killer cells in autoimmune liver disease: a comprehensive review

K Hudspeth, E Pontarini, P Tentorio, M Cimino… - Journal of …, 2013 - Elsevier
Natural Killer (NK) cells are important players of the innate arm of the immune system and
provide an early defense against pathogens and tumor-transformed cells. Peripheral blood …

Complications, symptoms, quality of life and pregnancy in cholestatic liver disease

K Zakharia, A Tabibian, KD Lindor… - Liver …, 2018 - Wiley Online Library
Cholestatic liver diseases (CLD s) encompass a variety of disorders of bile formation and/or
flow which generally result in progressive hepatobiliary injury and ultimately end‐stage liver …

Hepatocellular carcinoma in primary biliary cholangitis

AM Sy, RD Ferreira, BV John - Clinics in Liver Disease, 2022 - liver.theclinics.com
Primary biliary cholangitis (PBC), formerly known as primary biliary cirrhosis, is an
autoimmune, T-cell-mediated condition affecting the biliary epithelial cells. It presents in a …

Sex-related factors in autoimmune liver diseases

D Schwinge, C Schramm - Seminars in immunopathology, 2019 - Springer
Autoimmune diseases are a broad range of diseases in which the immune system produces
an inappropriate response to self-antigens. This results in inflammation, damage, or …

Metabolic signature of primary biliary cholangitis and its comparison with celiac disease

A Vignoli, B Orlandini, L Tenori… - Journal of proteome …, 2018 - ACS Publications
Primary biliary cholangitis (PBC) is a chronic autoimmune liver disease characterized by
ongoing inflammatory destruction of the interlobular bile ducts, eventually leading to chronic …