Type 2 Diabetes is a major public health threat, and its prevalence is increasing worldwide.
The abnormal accumulation of islet amyloid polypeptide (IAPP) in pancreatic β-cells is …

Barnacles are unique marine sessile crustaceans and permanently attach to various foreign
surfaces during most of their lifespan. The protein complex secreted from their body and …

Ethnopharmacological relevance Danshen, is a traditional Chinese medicine obtained from
the dried root and rhizome of Salvia miltiorrhiza Bunge. It is known to be used for …

Experimentally, short peptides have been shown to form amyloids similar to those of their
parent proteins. Consequently, they present useful systems for studies of amyloid …

We present a protein engineering analysis of the fibrillation of a protein from a thermophilic
organism, the 101 residue S6 from Thermus thermophilus. When agitated, S6 fibrillates at …

Amyloids are proteinaceous fibers commonly associated with neurodegenerative diseases
and prion-based encephalopathies. Many different polypeptides can form amyloid fibers …

Aromatic residues have been previously shown to mediate the self-assembly of different
soluble proteins through π-π interactions (McGaughey, GB, Gagne, M., and Rappe, AK …

The hexapeptide NFGAIL is a highly amyloidogenic peptide, derived from the human islet
amyloid polypeptide (hIAPP). Recent investigations indicate that presumably soluble hIAPP …

Protein aggregation is involved in several human diseases, and presumed to be an
important process in protein quality control. In bacteria, aggregation of proteins occurs …

Aromatic amino acids strongly promote cross‐β amyloid formation; whether the
amyloidogenicity of aromatic residues is due to high hydrophobicity and β‐sheet propensity …