Background The prevalence of depression has been increasing worldwide in recent years,
posing a heavy burden on patients and society. However, the diagnostic and therapeutic …

Major depressive disorder (MDD) is a devastating mental illness and the leading cause of
disability worldwide. Previous studies have suggested that synaptic plasticity in the …

Objective Energy metabolism plays a crucial role in the improvement of heart dysfunction as
well as the development of heart failure (HF). The current study is designed to identify …

Astrocytic dysfunction contributes to the molecular pathogenesis of major depressive
disorder (MDD). However, the astrocytic subtype that mainly contributes to MDD etiology …

Background Several lines of evidence point to an interaction between genetic predisposition
and environmental factors in the onset of major depressive disorder (MDD). This study is …

Alterations in subcortical brain structure volumes have been found to be associated with
several neurodegenerative and psychiatric disorders. At the same time, genome-wide …

Proteomics has been widely used to investigate multiple diseases. Combining the analyses
of proteomics with phosphoproteomics can be used to further explain the pathological …