Morphine is the most commonly used opioid for severe cancer-related pain. Despite its
established effectiveness, it is often used cautiously in clinical practice, particularly outside …

Breast cancer is one of the most prevalent cancers amongst women in the world.
Unfortunately, even after adequate treatment, some patients experience severe pain either …

The Research Network of the European Association for Palliative Care (EAPC) performed a
survey of 3030 cancer patients from 143 palliative care centres in 21 European countries …

Background: This topical review addresses methadone's pharmacology, its application in
malignant and non‐malignant pain conditions, practical issues related to methadone for the …

PURPOSE: The aim of this study was to compare the analgesic and adverse effects, doses,
as well as cost of opioid drugs, supportive drug therapy and other analgesic drugs in …

Background Many patients with cancer experience moderate to severe pain that requires
treatment with strong analgesics. Buprenorphine, fentanyl and morphine are examples of …

Pain is a prevalent symptom experienced by at least 30% of patients undergoing an
oncological treatment for metastatic disease and by more than 70% of advanced cancer …

Background: To assess the adverse effects of transdermal opiates treating moderate-severe
cancer pain in comparison with slow release oral morphine. Methods: A systematic review of …

Background Intrathecal opioids are routinely administered during spinal anesthesia for
postcesarean analgesia. The effectiveness of intrathecal morphine for postcesarean …

Background: Nonsteroidal anti-inflammatory drugs (NSAIDs) and paracetamol are used
widely in the management of mild to moderate cancer pain and are frequently combined …