Important insights into leukocyte differentiation and the cellular origins of leukemia and
lymphoma have been gained through the use of monoclonal antibodies that define cell …

Most human lymphoid malignancies preserve a pattern of gene expression reflecting their
proliferative activity and the developmental level of clonal expansion and maturation arrest …

In 76 muscle specimens (normal controls, 9; Duchenne dystrophy, 11; scleroderma, 11;
dermatomyositis, 13; polymyositis, 15; inclusion body myositis, 17), mononuclear cells were …

The chronic fatigue syndrome (CFS), formerly known as chronic Epstein-Barr virus
syndrome, is a clinical state of some complexity and uncertain etiology. In order to …

Immunocompetent cells in exacerbating untreated psoriasis vulgaris skin lesions were
immunophenotypically studied by the application of a selection of monoclonal antibodies in …

Ionic fluxes are thought to he involved in mediating the prolifer-ation of peripheral blood
lymphocytes (PBLs) in response to mitogenic substances1, 2. Among the earliest events …

Monoclonal antibodies reactive for B cells, T cells, T-cell subsets, killer (K) and natural killer
(NK) cells, and the Ia antigen were used to analyzed mononuclear cell subsets in …

Oral doses of beta-carotene (180 mg/day) given for 2 wk to normal human volunteers
significantly increased the frequency of OKT4+(helper/inducer T cells) after 7 days and of …

Tumor cells were isolated from the bone marrow of seven patients with multiple myeloma
and from the peripheral blood of three patients with plasma cell leukemia using Ficoll …

Viruses may cause immunosuppression by a variety of mechanisms. This review delineates
four categories. First, immunosuppression can result from the direct effects of viral replication …